Pancrelipase
Also known as: Viokase, Pancrezyme, Epizyme, Panakare, Pancrepowder Plus, Pancreved
### Important Handling Precautions > **WARNING:** Do not inhale the powder! It can cause severe mucous membrane irritation and may trigger asthma attacks in susceptible individuals. * If powder spills on your hands, wash it off immediately to prevent skin irritation. Do not allow the powder to contact your eyes. ### Administration Tips * **Lifelong Therapy:** Exocrine Pancreatic Insufficiency (EPI) is typically a permanent condition. Your pet will likely need this supplement with *every* meal for the rest of their life. * **Mixing:** Mix the powder thoroughly with moistened food. Some veterinarians recommend letting the mixture sit for 15-20 minutes before feeding to help pre-digest the food and reduce the risk of mouth ulcers. * **Cats:** Cats often dislike the taste of the powder. If your cat refuses to eat it, your veterinarian may recommend putting the powder into capsules. Always follow capsules with food or water to prevent esophageal damage. ### What to Watch For * **Side Effects:** Watch for oral bleeding or mouth sores. If you notice this, contact your vet—they may recommend moistening the food more or adjusting the dose. * **Monitoring:** Keep track of your pet's weight and stool quality. Successful treatment will result in weight gain and normal, firm stools.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Pancreatic exocrine insufficiency
- Pancreatic exocrine insufficiency
- Pancreatic exocrine insufficiency
- Pancreatic exocrine insufficiency
- Pancreatic exocrine insufficiency
- Gastric trichobezoars (Rabbits)
- Pancreatic exocrine insufficiency
- Pancreatic exocrine insufficiency
- Pancreatic exocrine insufficiency
- Pancreatic exocrine insufficiency
How it is given
Possible side effects
- GI distress (diarrhea, cramping, nausea) at high doses
- Oral or esophageal ulcers (from concentrated enzymes)
- Oral bleeding (reported in dogs)
Cautions & contraindications
- Hypersensitivity to pork proteins
- **Do not inhale the powder**, as bronchial/lung irritation can occur and it may trigger asthma attacks in susceptible individuals. Avoid contact with mucous membranes or skin. Wash hands after handling. To prevent oral or esophageal ulcers, follow dosing with food or water. Moistening the food/powder mix may decrease the incidence of oral bleeding in dogs.
Drug interactions
- Antacids (magnesium hydroxide, calcium carbonate): May diminish the effectiveness of pancrelipase
- Cimetidine (or other H2 antagonists): May increase the amount of pancrelipase that reaches the duodenum
Frequently asked questions
What is Pancrelipase used for in pets?
### Important Handling Precautions > **WARNING:** Do not inhale the powder! It can cause severe mucous membrane irritation and may trigger asthma attacks in susceptible individuals. * If powder spills on your hands, wash it off immediately to prevent skin irritation. Do not allow the powder to contact your eyes. ### Administration Tips * **Lifelong Therapy:** Exocrine Pancreatic Insufficiency (EPI) is typically a permanent condition. Your pet will likely need this supplement with *every* meal for the rest of their life. * **Mixing:** Mix the powder thoroughly with moistened food. Some veterinarians recommend letting the mixture sit for 15-20 minutes before feeding to help pre-digest the food and reduce the risk of mouth ulcers. * **Cats:** Cats often dislike the taste of the powder. If your cat refuses to eat it, your veterinarian may recommend putting the powder into capsules. Always follow capsules with food or water to prevent esophageal damage. ### What to Watch For * **Side Effects:** Watch for oral bleeding or mouth sores. If you notice this, contact your vet—they may recommend moistening the food more or adjusting the dose. * **Monitoring:** Keep track of your pet's weight and stool quality. Successful treatment will result in weight gain and normal, firm stools.
Is Pancrelipase safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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