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Metergoline

Also known as: Contralac, Liserdol

Drug class: Serotonin Antagonist; Prolactin Inhibitor

> **Important:** Give this medication with food to help reduce stomach upset. - **Watch for side effects:** Your pet may experience nausea, vomiting, or changes in behavior (such as anxiety, whining, or escaping behavior). Contact your veterinarian if vomiting persists or behavioral changes are severe. - **Do not give to pregnant pets:** This medication can cause abortion. - Keep this and all medications securely out of reach of children and other pets.

Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.

Veterinary professional? See the full dosing-by-species reference on VetSheet →

What it is used for

  • Treatment of pseudopregnancy or to halt post-partum lactation
  • Treatment of pseudopregnancy
  • Treatment of pseudopregnancy
  • Treatment of pseudopregnancy
  • To induce estrus

How it is given

PO

Possible side effects

  • Anxiety
  • Aggressiveness
  • Depression
  • Hyperexcitation
  • Whining
  • Escaping behavior
  • Anorexia
  • Vomiting
  • Nausea

Cautions & contraindications

  • Pregnancy (unless abortion is desired)
  • Nursing mothers
  • Hypersensitivity to ergot derivatives
  • Use with caution in patients with significantly impaired liver function; a lower dosage may be required. Patients that do not tolerate cabergoline or bromocriptine may or may not tolerate metergoline. **Do not use in pregnant animals** unless pregnancy termination is the specific clinical goal.

Drug interactions

  • Bromocriptine: May cause additive effects if used with metergoline
  • Cabergoline: May cause additive effects if used with metergoline
  • Cyproheptadine: May cause additive effects if used with metergoline
  • Metoclopramide: Use with metergoline may reduce the efficacy of both drugs and should be avoided
  • SSRIs (e.g., fluoxetine, paroxetine, sertraline): Potentially could reduce the efficacy of each drug

Frequently asked questions

What is Metergoline used for in pets?

> Important: Give this medication with food to help reduce stomach upset. - Watch for side effects: Your pet may experience nausea, vomiting, or changes in behavior (such as anxiety, whining, or escaping behavior). Contact your veterinarian if vomiting persists or behavioral changes are severe. - Do not give to pregnant pets: This medication can cause abortion. - Keep this and all medications securely out of reach of children and other pets.

Is Metergoline safe for my pet?

Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.

This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.

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