Lufenuron
Also known as: Program, Sentinel
> **Crucial Administration Step:** You **must** give this medication with a full meal (preferably containing some fat). If given on an empty stomach, the body will not absorb it properly, and it will not work. - **How it works:** This drug is like "birth control" for fleas. It does not kill the adult fleas currently jumping on your pet, but it stops their eggs from hatching. - **Patience is key:** It may take 2 to 3 months to see a complete reduction in the flea population in your home. You may need a separate medication to kill the adult fleas in the meantime. - **Treat all pets:** Every dog and cat in the household must be on flea prevention, or the flea life cycle will continue. - **Missed doses:** Must be used every 30 days to maximize efficacy. If a dose is missed, give it as soon as you remember and resume the monthly schedule. - **Vomiting:** If your pet vomits within 2 hours of taking the pill, they will need to be re-dosed. - **Do not split tablets.**
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Control of flea populations
- Adjunctive therapy for dermatophytosis
- E. cuniculi infections / Flea control
- Control of flea populations
- Adjunctive therapy for dermatophytosis
How it is given
Possible side effects
- Vomiting
- Lethargy or depression
- Pruritus or urticaria
- Diarrhea
- Dyspnea
- Anorexia
- Reddened skin
- Small lump at injection site (cats receiving injectable formulation)
Cautions & contraindications
- The cat-labeled injectable product should NOT be used in dogs (severe local reactions are possible)
- **Administration Warning:** Oral lufenuron **must** be given with or immediately after a full, fatty meal to ensure adequate absorption. **Species Warning:** Do not use the 6-month feline injectable formulation in dogs due to the risk of severe local tissue reactions. **Expectation Management:** Owners must be warned that lufenuron does not kill adult fleas. Untreated animals in the same environment will perpetuate the flea life cycle.
Frequently asked questions
What is Lufenuron used for in pets?
> **Crucial Administration Step:** You **must** give this medication with a full meal (preferably containing some fat). If given on an empty stomach, the body will not absorb it properly, and it will not work. - **How it works:** This drug is like "birth control" for fleas. It does not kill the adult fleas currently jumping on your pet, but it stops their eggs from hatching. - **Patience is key:** It may take 2 to 3 months to see a complete reduction in the flea population in your home. You may need a separate medication to kill the adult fleas in the meantime. - **Treat all pets:** Every dog and cat in the household must be on flea prevention, or the flea life cycle will continue. - **Missed doses:** Must be used every 30 days to maximize efficacy. If a dose is missed, give it as soon as you remember and resume the monthly schedule. - **Vomiting:** If your pet vomits within 2 hours of taking the pill, they will need to be re-dosed. - **Do not split tablets.**
Is Lufenuron safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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