Estriol
Also known as: Incurin
Administer this medication exactly as directed by your veterinarian. > **Important Safety Warning:** Pregnant or breastfeeding women should handle this medication with caution (wear gloves or wash hands immediately after handling). Monitor your dog for signs of 'heat' (such as a swollen vulva or being attractive to male dogs) and report these to your vet. Do not exceed the prescribed dose, as high doses can cause serious blood disorders.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
- All indications
- Urethral sphincter mechanism incompetence (USMI) in spayed bitches
How it is given
Possible side effects
- Oestrogenic effects (swollen vulva, attractiveness to males) in 5-9% of dogs at 2 mg/day
- Bone marrow suppression (rare, but possible with long-term use)
- Gastrointestinal upset (mild)
Cautions & contraindications
- Intact bitches
- Polyuria/polydipsia (PU/PD) of unknown origin
- Animals < 1 year old
- > **Human Safety Warning:** Pregnant or breastfeeding women should handle this medication with caution. Wash hands after administration or wear gloves.
Drug interactions
- Phenylpropanolamine: Concurrent administration may potentiate efficacy in treating urinary incontinence (synergistic effect).
Frequently asked questions
What is Estriol used for in pets?
Administer this medication exactly as directed by your veterinarian. > Important Safety Warning: Pregnant or breastfeeding women should handle this medication with caution (wear gloves or wash hands immediately after handling). Monitor your dog for signs of 'heat' (such as a swollen vulva or being attractive to male dogs) and report these to your vet. Do not exceed the prescribed dose, as high doses can cause serious blood disorders.
Is Estriol safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
Worried about your pet?
Peqaboo’s AI helps you track symptoms, understand lab reports, and know when to see a vet.
Get the Peqaboo app