Emodepside and Praziquantel
Also known as: Profender
> **Important Application Instructions:** Apply the solution directly to the skin at the base of the cat's neck/head. This location minimizes the chance of the cat licking the product off while grooming. * **Do not** apply to broken skin or if the hair coat is wet. * **Prevent Licking:** Do not allow the cat to lick the application site for at least **one hour** after application. Oral exposure can cause drooling, vomiting, and tremors. * **Multi-Pet Households:** Keep treated animals separated from other pets for a short period to prevent them from grooming each other. * **Human Safety:** Not for human use. Keep out of reach of children. Children should not touch the application site for 24 hours. **Pregnant women**, or women who may become pregnant, should avoid direct contact with the product or wear disposable gloves during application.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Treatment and control of hookworm, roundworm, and tapeworm infections
- Parasitic infections (off-label)
How it is given
Possible side effects
- Application site reactions (alopecia, dermatitis, pyoderma, edema, erythema, pruritus)
- Salivation/hypersalivation (especially if licked)
- Lethargy
- Vomiting
- Diarrhea
- Agitation or nervousness
- Tremors or twitching
- Ataxia
- Eye or respiratory irritation
- Rare post-approval reports: facial swelling, rear leg paralysis, seizures, hyperesthesia, morphea-like (scleroderma) lesion
Cautions & contraindications
- Cats less than 8 weeks of age
- Cats weighing less than 1 kg (2.2 lb)
- Use with caution in sick, debilitated, or heartworm-positive cats. Safe use has not been evaluated in breeding, pregnant, or lactating queens (studies in laboratory animals suggest emodepside may interfere with fetal development). Do not apply to broken skin or wet hair coats. Prevent the patient or other animals from licking the application site for at least one hour.
Drug interactions
- P-glycoprotein inhibitors/substrates (e.g., ivermectin, erythromycin, prednisolone, cyclosporine): Emodepside is a P-glycoprotein substrate; concurrent use may cause pharmacokinetic interactions and potentially increase toxicity or alter efficacy.
Frequently asked questions
What is Emodepside and Praziquantel used for in pets?
> **Important Application Instructions:** Apply the solution directly to the skin at the base of the cat's neck/head. This location minimizes the chance of the cat licking the product off while grooming. * **Do not** apply to broken skin or if the hair coat is wet. * **Prevent Licking:** Do not allow the cat to lick the application site for at least **one hour** after application. Oral exposure can cause drooling, vomiting, and tremors. * **Multi-Pet Households:** Keep treated animals separated from other pets for a short period to prevent them from grooming each other. * **Human Safety:** Not for human use. Keep out of reach of children. Children should not touch the application site for 24 hours. **Pregnant women**, or women who may become pregnant, should avoid direct contact with the product or wear disposable gloves during application.
Is Emodepside and Praziquantel safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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