Danofloxacin
Also known as: A180, Advocin, Advocine, Danocin, Advocid, Advovet, Exocin
> **Important:** If administering to food animals, strict adherence to label directions is legally required. * Ensure proper subcutaneous (SC) injection technique. * Do not exceed 15 mL per injection site to minimize tissue damage. * Observe the mandatory 4-day slaughter withdrawal time from the last treatment. * Monitor the animal for any signs of lameness, neurological signs, or injection site reactions.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Ophthalmic infections
- Bovine Respiratory Disease (BRD)
- Ophthalmic infections
How it is given
Possible side effects
- Hypersensitivity reactions (uncommon)
- Lameness or arthropathies (especially in young animals/calves)
- Local tissue reaction at the subcutaneous injection site (may result in trim loss)
- Mild, transient ocular irritation or stinging upon application (general class effect)
- Conjunctival hyperemia (rare)
Cautions & contraindications
- Extra-label use in food-producing animals (FDA prohibited)
- Lactating dairy cattle (where milk is for human consumption)
- Veal calves
- Animals with known or suspected CNS disorders (relative contraindication)
- Known hypersensitivity to ofloxacin or other fluoroquinolones
- The FDA strictly prohibits extra-label usage of this drug in food animals. Use with caution in animals with known or suspected CNS disorders, as quinolones have rarely caused CNS stimulation. Do not use in lactating dairy cattle or calves to be processed for veal.
Drug interactions
- Theophylline (aminophylline): Potential increase in serum concentrations of theophylline; increased monitoring of theophylline concentrations is recommended
Frequently asked questions
What is Danofloxacin used for in pets?
> **Important:** If administering to food animals, strict adherence to label directions is legally required. * Ensure proper subcutaneous (SC) injection technique. * Do not exceed 15 mL per injection site to minimize tissue damage. * Observe the mandatory 4-day slaughter withdrawal time from the last treatment. * Monitor the animal for any signs of lameness, neurological signs, or injection site reactions.
Is Danofloxacin safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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