Corticotropin (ACTH)
Also known as: Acthar, Adrenomone, H.P. Acthar Gel
Your veterinarian is using this medication to perform an **ACTH stimulation test**, which evaluates how well your pet's adrenal glands are functioning. - **The Procedure**: The test involves drawing a baseline blood sample, giving an injection of the hormone, and then drawing another blood sample 1 to 2 hours later (or longer in horses). - **Safety**: > **Note:** This is a very safe diagnostic test. Side effects from a single dose are extremely rare. - **Preparation**: Ensure your veterinarian knows about all medications your pet is taking, especially any steroid medications (like hydrocortisone creams or pills), as these can interfere with the test results.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- ACTH Stimulation Test
- ACTH Stimulation Test
- ACTH deficiency or primary bovine ketosis
- ACTH Stimulation Test
- ACTH Stimulation Test
- ACTH Stimulation Test
- ACTH Stimulation Test
- ACTH Stimulation Test
How it is given
Possible side effects
- Fluid and electrolyte disturbances (with prolonged/chronic use)
- Hypersensitivity reactions (rare)
Cautions & contraindications
- Hypersensitivity to porcine proteins
- Intravenous (IV) administration of the repository gel formulation
- Do not administer the repository gel form intravenously (IV). Use cautiously during pregnancy (FDA Category C); it may be embryocidal, and benefits must outweigh risks. If used chronically (rare in veterinary medicine), potassium supplementation may be required.
Drug interactions
- Anticholinesterases (e.g., pyridostigmine): May antagonize effects in patients with myasthenia gravis
- Diuretics: May increase electrolyte loss (e.g., hypokalemia) if used chronically
- Glucocorticoids (hydrocortisone, cortisone): Exogenous administration on the day of the test will cross-react with cortisol assays and invalidate test results
Frequently asked questions
What is Corticotropin (ACTH) used for in pets?
Your veterinarian is using this medication to perform an **ACTH stimulation test**, which evaluates how well your pet's adrenal glands are functioning. - **The Procedure**: The test involves drawing a baseline blood sample, giving an injection of the hormone, and then drawing another blood sample 1 to 2 hours later (or longer in horses). - **Safety**: > **Note:** This is a very safe diagnostic test. Side effects from a single dose are extremely rare. - **Preparation**: Ensure your veterinarian knows about all medications your pet is taking, especially any steroid medications (like hydrocortisone creams or pills), as these can interfere with the test results.
Is Corticotropin (ACTH) safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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