Cloprostenol Sodium
Also known as: Estrumate, estroPLAN
> **CRITICAL HUMAN SAFETY WARNING:** Cloprostenol is readily absorbed through the skin and can cause severe adverse effects in humans. * **Pregnant women, women of child-bearing age, asthmatics, and individuals with bronchial diseases** must use **extreme caution** or avoid handling this product entirely. Accidental exposure can induce abortion or acute bronchospasm (asthma attack). * If accidental skin exposure occurs, **wash the area immediately** with soap and water. * This medication should only be handled and administered by individuals fully familiar with its use and safety precautions. * In dogs, you may notice side effects like drooling, vomiting, increased urination/defecation, or panting shortly after administration. Your veterinarian may prescribe an additional medication to help minimize these effects.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- To induce parturition in does
- To treat pseudopregnancy (hydrometra/mucometra)
- For treatment of pyometra
- For pyometra or chronic endometritis, mummified fetus, luteal cysts
- For unobserved or undetected estrus in cows with continued ovarian cyclicity and a mature corpus luteum
- For abortion, from one week after mating to approximately the 150th day of gestation
- For controlled breeding (Single injection method)
- For controlled breeding (Double injection method)
- To cause abortion prior to the twelfth day of gestation
- For luteolysis and to stimulate uterine contractions
- For luteolysis
- As an ecbolic
How it is given
Possible side effects
- Increased salivation (dogs)
- Tachycardia (dogs)
- Increased urination and defecation (dogs)
- Gagging and vomiting (dogs)
- Ataxia and mild depression (dogs)
- Sweating (horses)
- Cramping and loose stools (horses)
- Increased risk of dystocia if used after 5th month of gestation (cattle)
Cautions & contraindications
- Pregnancy (when abortion or induced parturition are not desired)
- Intravenous (IV) administration
- Women of child-bearing age, pregnant women, and persons with asthma or other respiratory diseases should use **extreme caution** when handling cloprostenol, as the drug may induce abortion or acute bronchoconstriction. Cloprostenol is readily absorbed through the skin and must be washed off immediately with soap and water. **Do not administer IV.**
Drug interactions
- Oxytocic agents: Activity may be enhanced by cloprostenol
Frequently asked questions
What is Cloprostenol Sodium used for in pets?
> **CRITICAL HUMAN SAFETY WARNING:** Cloprostenol is readily absorbed through the skin and can cause severe adverse effects in humans. * **Pregnant women, women of child-bearing age, asthmatics, and individuals with bronchial diseases** must use **extreme caution** or avoid handling this product entirely. Accidental exposure can induce abortion or acute bronchospasm (asthma attack). * If accidental skin exposure occurs, **wash the area immediately** with soap and water. * This medication should only be handled and administered by individuals fully familiar with its use and safety precautions. * In dogs, you may notice side effects like drooling, vomiting, increased urination/defecation, or panting shortly after administration. Your veterinarian may prescribe an additional medication to help minimize these effects.
Is Cloprostenol Sodium safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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