Cinchophen and Prednisolone
Also known as: PLT tablets, Prednoleucotropin, PLT
Administer strictly as directed by your veterinarian, ideally with food. > **Important:** Watch closely for signs of stomach ulcers, such as vomiting (especially with blood or looking like coffee grounds), dark tarry stools, or loss of appetite. Due to the steroid component, you may notice increased thirst, urination, and appetite. **Do not stop this medication abruptly** unless instructed by your vet, as the dose usually needs to be tapered slowly.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
How it is given
Possible side effects
- Gastrointestinal ulceration
- Hepatotoxicity
- Polyuria (PU)
- Polydipsia (PD)
- Polyphagia
- Vomiting
- Diarrhea
- Melena
Cautions & contraindications
- Pre-existing gastrointestinal ulceration
- Hepatic impairment
- Renal impairment
- Concurrent use of other NSAIDs or corticosteroids
- Animals must be strictly monitored for signs of **gastrointestinal ulceration** (e.g., melena, vomiting blood) and **deterioration in liver function**. > **Warning:** At the end of treatment, the dose must be tapered gradually to prevent Addisonian crisis due to adrenal suppression from the prednisolone component.
Drug interactions
- NSAIDs (other): Increased risk of severe GI ulceration and perforation
- Corticosteroids (other): Increased risk of severe GI ulceration and immunosuppression
- Other NSAIDs (e.g., Meloxicam, Carprofen): Synergistic toxicity leading to severe gastrointestinal ulceration and perforation.
- Other Corticosteroids (e.g., Dexamethasone): Synergistic toxicity leading to severe gastrointestinal ulceration and perforation.
- Furosemide: Increased risk of nephrotoxicity and gastrointestinal ulceration.
Frequently asked questions
What is Cinchophen and Prednisolone used for in pets?
Administer strictly as directed by your veterinarian, ideally with food. > **Important:** Watch closely for signs of stomach ulcers, such as vomiting (especially with blood or looking like coffee grounds), dark tarry stools, or loss of appetite. Due to the steroid component, you may notice increased thirst, urination, and appetite. **Do not stop this medication abruptly** unless instructed by your vet, as the dose usually needs to be tapered slowly.
Is Cinchophen and Prednisolone safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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