Aztreonam
Also known as: Azactam, Cayston, Monobac, Aztreotic, Azenam, Primbactam, Trezam, Urobactam
> **Important:** This medication should only be administered by veterinary professionals. * Because of the frequent dosing intervals required (every 6-8 hours), this drug is best administered to **inpatients** in a hospital setting. * If your pet is nursing, the drug is generally considered safe, but monitor the nursing offspring for signs of **antibiotic-associated diarrhea**.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
- Serious gram-negative infections
How it is given
Possible side effects
- Hypersensitivity reactions
- Gastrointestinal effects (bacterial overgrowth, pseudomembranous colitis, diarrhea)
- Pain and/or swelling after IM injection
- Phlebitis after IV administration
- Transient increases in liver enzymes, serum creatinine, and coagulation indices
Cautions & contraindications
- Documented severe hypersensitivity to aztreonam
- Use cautiously in patients with serious renal or liver dysfunction; dosage adjustment may be needed. Aztreonam may cause false-positive urine glucose determinations when using cupric sulfate solutions (e.g., Benedict's Solution, Clinitest). Tests utilizing glucose oxidase are not affected.
Drug interactions
- Probenecid: Can reduce the renal tubular secretion of aztreonam, thereby maintaining higher systemic levels for a longer period of time. This potential 'beneficial' interaction requires further investigation in veterinary patients.
Frequently asked questions
What is Aztreonam used for in pets?
> Important: This medication should only be administered by veterinary professionals. • Because of the frequent dosing intervals required (every 6-8 hours), this drug is best administered to inpatients in a hospital setting. • If your pet is nursing, the drug is generally considered safe, but monitor the nursing offspring for signs of antibiotic-associated diarrhea.
Is Aztreonam safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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