Aminocaproic Acid
Also known as: Amicar, Capracid, Capramol, Caproamin, Caprolisin, Epsicaprom, Hemocaprol, Hemocid, Hexalense, Ipsilon
* **Purpose**: Prescribed to prevent excessive bleeding or, historically, for a spinal cord disease called degenerative myelopathy. * **Cost**: Treatment can be very expensive, especially for large breed dogs like German Shepherds. * **Expectations**: If used for degenerative myelopathy, understand that this is considered *investigational* and recent studies show little to no benefit. Neurological signs may continue to worsen. * **Side Effects**: Occasionally causes mild stomach upset (vomiting, diarrhea). Contact your veterinarian if these occur or if you notice any unusual signs.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Adjunctive treatment of degenerative myelopathy (seen primarily in German shepherds)
- Antifibrinolytic
How it is given
Possible side effects
- GI irritation (vomiting, diarrhea) in ~1% of dogs
- Hyperkalemia (particularly in renal impaired patients)
Cautions & contraindications
- Active intravascular clotting (e.g., Disseminated Intravascular Coagulation - DIC)
- > **WARNING**: Aminocaproic acid is absolutely contraindicated in patients with active **Disseminated Intravascular Coagulation (DIC)** or active intravascular clotting, as it can lead to fatal thrombosis. * Use only when benefits outweigh risks in patients with preexisting **cardiac, renal, or hepatic disease**. * May cause **hyperkalemia**, particularly in patients with renal impairment. * **Pregnancy**: FDA Category C. Some animal studies have demonstrated teratogenicity; use only when the risk-to-benefit ratio merits.
Drug interactions
- Estrogens: Hypercoagulation states may occur in patients receiving aminocaproic acid and estrogens concurrently.
Frequently asked questions
What is Aminocaproic Acid used for in pets?
* **Purpose**: Prescribed to prevent excessive bleeding or, historically, for a spinal cord disease called degenerative myelopathy. * **Cost**: Treatment can be very expensive, especially for large breed dogs like German Shepherds. * **Expectations**: If used for degenerative myelopathy, understand that this is considered *investigational* and recent studies show little to no benefit. Neurological signs may continue to worsen. * **Side Effects**: Occasionally causes mild stomach upset (vomiting, diarrhea). Contact your veterinarian if these occur or if you notice any unusual signs.
Is Aminocaproic Acid safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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