氨苯蝶啶
別名: Dyrenium, Dytac, Dyazide, Maxzide, Triteren
藥物類別: Potassium-Sparing Diuretic
* **給藥方式**：請隨餐給予此藥物，以幫助減少腸胃不適。 * **尿液顏色**：服藥期間，您寵物的尿液可能會呈現**藍色**，這是正常且無害的現象。 * **監測**：由於此藥物在犬貓中並不常用，請密切觀察您的寵物，若發現任何異常反應（如嚴重喺睡、虛弱或嘔吐），請立即通知獸醫師。 * **飲食限制**：除非獸醫師特別指示，否則請勿給予寵物鋎補充劑或高鋎食物/零食。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Adjunctive treatment of recurrent heart failure associated with chronic mitral valve insufficiency
- As a diuretic for adjunctive treatment of CHF
給藥方式
PO
可能的副作用
- Hyperkalemia (most significant risk)
- Gastrointestinal upset
- Hyponatremia
- Headache or dizziness (reported in humans)
- Increased sensitivity to sunlight
- Hypersensitivity reactions (rare)
- Nephrolithiasis (rare)
- Blood dyscrasias such as agranulocytosis, thrombocytopenia, or megaloblastosis (rare)
注意事項與禁忌
- Anuria
- Severe or progressive renal disease
- Severe hepatic disease
- Hypersensitivity to triamterene
- Preexisting hyperkalemia or history of triamterene-induced hyperkalemia
- Concurrent therapy with another potassium-sparing agent (e.g., spironolactone, amiloride)
- Concurrent potassium supplementation
- > **Warning**: Hyperkalemia is a definite possibility. Monitoring of electrolytes and renal function is strictly necessary. * **Renal Function**: May slightly reduce GFR (reversible upon discontinuation). Use with caution in patients with compromised renal blood flow. * **Pregnancy**: Crosses the placental barrier. Animal studies (rats) at 6-20X human dose showed no adverse fetal effects, but adequate studies are lacking. Weigh potential benefits against risks. * **Lactation**: Distributed into milk. Safety during nursing cannot be assured.
藥物相互作用
- ACE Inhibitors (e.g., enalapril, benazepril): Increased risks for hyperkalemia.
- Antidiabetic Agents (insulin, oral hypoglycemics): Triamterene may increase blood glucose levels.
- Antihypertensive Agents: Possible potentiation of hypotensive effects.
- Diuretics, Potassium-Sparing (spironolactone, amiloride): Increased risk of hyperkalemia; concurrent use is contraindicated.
- Lithium: Triamterene may reduce lithium clearance, increasing the risk of lithium toxicity.
- NSAIDs (especially indomethacin): May increase the risks of nephrotoxicity when used concurrently.
- Potassium Supplements or High Potassium Foods: Increased risk for hyperkalemia.
- Quinidine: Laboratory interaction: Triamterene may interfere with the fluorescent assay of quinidine.
常見問題
氨苯蝶啶用於寵物有什麼用途？
* **給藥方式**：請隨餐給予此藥物，以幫助減少腸胃不適。 * **尿液顏色**：服藥期間，您寵物的尿液可能會呈現**藍色**，這是正常且無害的現象。 * **監測**：由於此藥物在犬貓中並不常用，請密切觀察您的寵物，若發現任何異常反應（如嚴重喺睡、虛弱或嘔吐），請立即通知獸醫師。 * **飲食限制**：除非獸醫師特別指示，否則請勿給予寵物鋎補充劑或高鋎食物/零食。
氨苯蝶啶對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。