多殺菌素
別名: Comfortis, Natroba, Extinosad, Trifexis
藥物類別: Antiparasitic - Oral Flea Adulticide (Macrocyclic Lactone)
### 給藥指南 * **隨餐餵食：** 必須與食物一起服用，藥物才能被狗狗的身體充分吸收。 * **嘔吐處理：** 如果狗狗在服藥後一小時內嘔吐，您應該再給予一次完整劑量以確保防護效果。 * **忘記服藥：** 如果忘記給藥，請在想起來時盡快隨餐補餵，然後從該日期起恢復每月一次的給藥計畫。 > **重要提示：** 這些咀嚼錠雖然是牛肉口味，但實際上含有豬肉蛋白和水解大豆。如果您的狗狗對豬肉或大豆有已知的食物過敏，請務必告知您的獸醫師。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Flea infestation
- Prevention or treatment of fleas infestations
- Flea infestation
給藥方式
POTopical (human use)
可能的副作用
- Vomiting (most common)
- Depression/lethargy
- Anorexia
- Ataxia
- Diarrhea
- Pruritus
- Trembling
- Hypersalivation
- Seizures (rare)
- Vomiting (occasional)
- Lethargy (rare)
- Diarrhoea (rare)
- Anorexia (rare)
- Ataxia (rare)
注意事項與禁忌
- Cats (per this specific monograph's label status)
- Dogs with known pork or soy allergies (chewable tablets contain pork proteins and hydrolyzed soy)
- Dogs and cats weighing < 1.2 kg
- Dogs and cats < 14 weeks of age
- Dogs with MDR1 mutation (relative contraindication due to increased risk of adverse effects)
- Use with caution in **breeding females** and dogs with **pre-existing epilepsy**, as higher than labeled dosages may decrease the seizure threshold. Safe use in breeding males has not been evaluated. The chewable tablets contain pork proteins and hydrolyzed soy; use cautiously in dogs with severe food allergies to these ingredients.
藥物相互作用
- Ivermectin: Concurrent use with high extra-label doses of ivermectin (e.g., for demodicosis) increases the risk of neurotoxicity. However, spinosad is safe to use with standard low-dose heartworm preventatives.
- Macrocyclic lactones (e.g., avermectins, ivermectin): Increased risk of severe neurological toxicity. Do not use in combination.
- Digoxin: Competition for P-glycoprotein efflux pump, potentially increasing digoxin levels.
- Doxorubicin: Competition for P-glycoprotein efflux pump, potentially increasing doxorubicin toxicity.
常見問題
多殺菌素用於寵物有什麼用途？
### 給藥指南 • 隨餐餵食： 必須與食物一起服用，藥物才能被狗狗的身體充分吸收。 • 嘔吐處理： 如果狗狗在服藥後一小時內嘔吐，您應該再給予一次完整劑量以確保防護效果。 • 忘記服藥： 如果忘記給藥，請在想起來時盡快隨餐補餵，然後從該日期起恢復每月一次的給藥計畫。 > 重要提示： 這些咀嚼錠雖然是牛肉口味，但實際上含有豬肉蛋白和水解大豆。如果您的狗狗對豬肉或大豆有已知的食物過敏，請務必告知您的獸醫師。
多殺菌素對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。