Spinosad
別名: Comfortis, Natroba, Extinosad, Trifexis
### Administration Guidelines * **Give with a full meal:** Food is required for the medication to be properly absorbed into your dog's system. * **Vomiting:** If your dog vomits within one hour of taking the tablet, you should give another full dose to ensure they are protected. * **Missed Doses:** If you forget a dose, give it with food as soon as you remember, and then resume your normal once-a-month schedule from that new date. > **Important Note:** These chewable tablets are beef-flavored but actually contain pork proteins and hydrolyzed soy. If your dog has a known food allergy to pork or soy, please inform your veterinarian.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Flea infestation
- Prevention or treatment of fleas infestations
- Flea infestation
給藥方式
可能的副作用
- Vomiting (most common)
- Depression/lethargy
- Anorexia
- Ataxia
- Diarrhea
- Pruritus
- Trembling
- Hypersalivation
- Seizures (rare)
- Vomiting (occasional)
- Lethargy (rare)
- Diarrhoea (rare)
- Anorexia (rare)
- Ataxia (rare)
注意事項與禁忌
- Cats (per this specific monograph's label status)
- Dogs with known pork or soy allergies (chewable tablets contain pork proteins and hydrolyzed soy)
- Dogs and cats weighing < 1.2 kg
- Dogs and cats < 14 weeks of age
- Dogs with MDR1 mutation (relative contraindication due to increased risk of adverse effects)
- Use with caution in **breeding females** and dogs with **pre-existing epilepsy**, as higher than labeled dosages may decrease the seizure threshold. Safe use in breeding males has not been evaluated. The chewable tablets contain pork proteins and hydrolyzed soy; use cautiously in dogs with severe food allergies to these ingredients.
藥物相互作用
- Ivermectin: Concurrent use with high extra-label doses of ivermectin (e.g., for demodicosis) increases the risk of neurotoxicity. However, spinosad is safe to use with standard low-dose heartworm preventatives.
- Macrocyclic lactones (e.g., avermectins, ivermectin): Increased risk of severe neurological toxicity. Do not use in combination.
- Digoxin: Competition for P-glycoprotein efflux pump, potentially increasing digoxin levels.
- Doxorubicin: Competition for P-glycoprotein efflux pump, potentially increasing doxorubicin toxicity.
常見問題
Spinosad用於寵物有甚麼用途？
### Administration Guidelines * **Give with a full meal:** Food is required for the medication to be properly absorbed into your dog's system. * **Vomiting:** If your dog vomits within one hour of taking the tablet, you should give another full dose to ensure they are protected. * **Missed Doses:** If you forget a dose, give it with food as soon as you remember, and then resume your normal once-a-month schedule from that new date. > **Important Note:** These chewable tablets are beef-flavored but actually contain pork proteins and hydrolyzed soy. If your dog has a known food allergy to pork or soy, please inform your veterinarian.
Spinosad對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。