哌拉西林鈉
別名: Pipracil, Pipril
藥物類別: Antibiotic - Extended Spectrum Penicillin
* **住院使用**：因為此藥物必須透過注射（靜脈、肌肉或皮下）給藥，且需要頻繁投藥，通常會在您的寵物住院期間由醫療人員施打。 * **用途**：這是一種強效抗生素，通常保留用於嚴重感染或對一般常見藥物具有抗藥性的細菌感染。 * **副作用**：整體而言非常安全。如果您的寵物曾對青黴素或頭孢菌素類抗生素有過敏反應，請務必告知獸醫師。偶爾可能會引起輕微的腸胃不適或腹瀉。 * **注射部位疼痛**：如果採用肌肉注射，注射當下可能會產生短暫的疼痛感。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- For bacteremia with or without endocarditis
- For respiratory infections
- For susceptible infections
- For Bordetella avium infections
- For susceptible infections
- For empirical treatment in Psittacines of gram-negative bacterial infections
- For bacteremia with or without endocarditis
- For respiratory infections
- For systemic treatment of otitis media or proliferative otitis externa complicated by gram-negative (especially Pseudomonas) bacteria
- For susceptible infections
- For susceptible infections (Snakes)
給藥方式
IVIMSC
可能的副作用
- Hypersensitivity reactions (allergic reactions)
- Local tissue irritation, pain at IM injection site
- Thrombophlebitis (with IV administration)
- Antibiotic-associated diarrhea (due to alterations in gut flora)
- Coagulation abnormalities (rare, mostly in renal failure)
- Neurotoxicity/seizures (at very high doses or in renal impairment)
- Clostridium difficile superinfections (rare)
注意事項與禁忌
- Patients with documented hypersensitivity to beta-lactam antibiotics (penicillins, cephalosporins)
- > **High Sodium Content**: Because of its sodium content (1.85 mEq per gram), high dosages may adversely affect patients with cardiac failure or hypernatremic conditions. * **Renal Impairment**: Dosage adjustment may be required in patients with significantly decreased renal function (CrCl <40 mL/min) to prevent neurotoxicity or coagulopathies. * **Laboratory Interference**: May cause false-positive urine glucose tests (cupric sulfate method) and false-positive direct Coombs' tests. Can falsely decrease aminoglycoside serum concentrations if samples are stored together prior to analysis.
藥物相互作用
- Aminoglycosides (amikacin, gentamicin, tobramycin): Synergistic against certain bacteria in vitro, but penicillins can chemically inactivate aminoglycosides in vivo (especially in renal failure or at massive doses). Do not mix in the same syringe/bag.
- Anticoagulants (heparin, warfarin): Piperacillin may rarely affect platelets; increased monitoring of coagulation parameters is suggested.
- Methotrexate: Piperacillin may increase methotrexate serum levels.
- Probenecid: Reduces renal tubular secretion of piperacillin, maintaining higher systemic levels for longer periods.
- Vecuronium: Piperacillin may prolong neuromuscular blockade.
常見問題
哌拉西林鈉用於寵物有什麼用途？
* **住院使用**：因為此藥物必須透過注射（靜脈、肌肉或皮下）給藥，且需要頻繁投藥，通常會在您的寵物住院期間由醫療人員施打。 * **用途**：這是一種強效抗生素，通常保留用於嚴重感染或對一般常見藥物具有抗藥性的細菌感染。 * **副作用**：整體而言非常安全。如果您的寵物曾對青黴素或頭孢菌素類抗生素有過敏反應，請務必告知獸醫師。偶爾可能會引起輕微的腸胃不適或腹瀉。 * **注射部位疼痛**：如果採用肌肉注射，注射當下可能會產生短暫的疼痛感。
哌拉西林鈉對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。