戊聚糖多硫酸鈉

用途

• Persistent or recurrent FLUTD
• Persistent or recurrent FLUTD
• Osteoarthritis
• Osteoarthritis
• Osteoarthritis (High loading dose for treatment of OA signs of pain, lameness and stiffness)
• Osteoarthritis (Medium Loading dose for management of OA after joint surgery)
• Osteoarthritis (Maintenance dose)
• Osteoarthritis

給藥方式

可能的副作用

• Vomiting
• Anorexia
• Lethargy
• Mild depression
• Bleeding or prolonged coagulation times (dose-dependent increase in PTT in horses)
• Transient increases in liver enzymes (reported in humans)

注意事項與禁忌

• Known hypersensitivity to pentosan polysulfate sodium
• Patients with active bleeding disorders
• Use with caution prior to surgery
• > **Bleeding Risk:** Because pentosan has mild anticoagulant properties, bleeding is possible in any species. Use with extreme caution in animals receiving other drugs that affect coagulation or those undergoing stressful exercise or surgery. * **Oral Administration in Cats:** Dosing twice daily can be stressful for both the cat and the owner. * **Surgical Procedures:** Consider withholding treatment prior to major surgical interventions due to the potential for increased surgical bleeding.

藥物相互作用

• NSAIDs (e.g., carprofen, meloxicam): May increase the risk of bleeding due to concurrent effects on coagulation and platelet function; use cautiously.
• Aspirin: Increased risk of bleeding due to combined anticoagulant and antiplatelet effects.
• Heparin: Additive anticoagulant effects; increased risk of hemorrhage.

常見問題