複方樟腦鴉片酊 (Paregoric)

用途

• Maldigestion, malabsorption, anti-diarrheal
• Antidiarrheal
• Antidiarrheal
• Acute colitis
• Maldigestion; malabsorption; antidiarrheal
• Antidiarrheal

給藥方式

可能的副作用

• Dogs: Constipation, bloat, sedation, paralytic ileus, toxic megacolon, pancreatitis, CNS effects
• Cats: Excitatory behavior (controversial use)
• Horses: Delayed clearance of GI microbes, prolonged febrile state

注意事項與禁忌

• Known hypersensitivity to narcotic analgesics
• Patients receiving monoamine oxidase inhibitors (MAOIs)
• Diarrhea caused by toxic ingestion (until the toxin is eliminated from the GI tract)
• > **Diagnostic Warning:** Opiates may obscure the diagnosis or clinical course of acute abdominal conditions (e.g., colic). * **Hepatic Disease:** Use with extreme caution in patients with hepatic encephalopathy; hepatic coma may result. * **Respiratory Disease:** Use with extreme caution in patients suffering from respiratory disease or acute respiratory dysfunction (e.g., pulmonary edema secondary to smoke inhalation). * **General Cautions:** Use cautiously in patients with hypothyroidism, severe renal insufficiency, adrenocortical insufficiency (Addison's disease), head injuries, increased intracranial pressure, and in geriatric or severely debilitated patients. * **Infectious Diarrhea:** May enhance bacterial proliferation and delay pathogen clearance.

藥物相互作用

• CNS Depressants (anesthetics, antihistamines, phenothiazines, barbiturates, tranquilizers, alcohol): May cause increased CNS or respiratory depression when used concurrently.
• Monoamine Oxidase Inhibitors (MAOIs, e.g., amitraz, selegiline): Contraindicated. Opiates should not be used for at least 14 days after receiving MAOIs due to the risk of severe, potentially fatal reactions.

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