氧四環黴素（眼用）

用途

• Chlamydial/Mycoplasma keratoconjunctivitis
• Susceptible infections (when no other agent is suitable)
• Susceptible infections
• Susceptible infections

給藥方式

可能的副作用

• Local irritation
• Hypersensitivity reactions (rare)
• Potential for overgrowth of non-susceptible organisms (e.g., fungi) with prolonged use
• Vomiting
• Diarrhoea
• Depression
• Hepatotoxicity (rare)
• Fever
• Hypotension (following IV administration)
• Anorexia (especially in cats)
• Superinfections (with prolonged use)
• Renal tubular functional changes
• Teeth staining in developing animals

注意事項與禁忌

• Known hypersensitivity to tetracyclines or polymyxin B
• Use of concentrated cattle/sheep depot formulations in small animals
• Pregnancy (last 2-3 weeks)
• Neonates (first month of life)
• Use in cats unless absolutely necessary
• Expect potential recurrence after discontinuation of topical treatment from organisms dormant in the nasal passage. Oral doxycycline is considered a better treatment to eliminate the carrier state of Chlamydia in cats.

藥物相互作用

• Penicillins: Bactericidal action of penicillins may be inhibited by oxytetracycline
• Antacids (Mg, Ca, Al): Binds tetracycline, significantly reducing its GI absorption
• Food or Milk products: Binds tetracycline, reducing its absorption
• Methoxyflurane: May increase the nephrotoxic effects
• Theophylline: GI effects of tetracyclines may be increased

常見問題