萘普生
別名: Naprosyn, Aleve, Anaprox, EC-Naprosyn, Midol Extended Relief, Naprelan, Equiproxen
藥物類別: Nonsteroidal Antiinflammatory Agent (NSAID)
> **危險警告**：絕對不要在沒有獸醫師明確指示的情況下，將人類的非處方止痛藥（如 Aleve®）給予您的寵物。萘普生對狗和貓具有高度毒性。 * 如果您的寵物被處方了萘普生，請嚴格遵守給藥時間表（對狗而言，給藥頻率可能低至每兩天一次）。 * 如果您發現以下情況，**請立即停藥並聯繫您的獸醫師**： * 食慾不振或精神沉鬱 * 嘔吐（特別是含有血液或看起來像咖啡渣的嘔吐物） * 腹瀉或排出黑色柏油狀糞便 * 飲水或排尿習慣改變
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Myositis and soft tissue diseases of the musculoskeletal system
- Systemic therapies for joint disease
- Septic arthritis pain; inflammation (Rabbits)
- Osteoarthritis and musculoskeletal inflammatory diseases (Last resort)
給藥方式
POIV
可能的副作用
- GI distress (anorexia, vomiting, diarrhea)
- Gastrointestinal ulcers and perforation
- Melena and bloody vomitus
- Renal effects (nephritis, nephrotic syndrome, fluid retention)
- Hepatic effects (increased liver enzymes)
- Hematologic effects (hypoproteinemia, decreased hematocrit, anemia)
- CNS effects (neuropathies, lethargy, depression)
注意事項與禁忌
- Active GI ulcers
- History of hypersensitivity to naproxen or other NSAIDs
- Pre-existing hematologic, renal, or hepatic disease
- > **WARNING**: Extremely narrow therapeutic index in dogs. Use is generally discouraged unless all FDA-approved, safer NSAIDs have failed. * **Relatively Contraindicated**: Patients with a history of or pre-existing hematologic, renal, or hepatic disease. * **Caution**: Use cautiously in patients with a history of GI ulcers or heart failure (may cause fluid retention). * **Infection**: Animals suffering from inflammation secondary to concomitant infection should receive appropriate antimicrobial therapy alongside NSAID treatment.
藥物相互作用
- Aminoglycosides (gentamicin, amikacin): Increased risk for nephrotoxicity
- Anticoagulants (heparin, LMWH, warfarin): Increased risk for bleeding
- Aspirin: Decreased plasma levels of naproxen and increased likelihood of GI adverse effects (blood loss). Concomitant use is not recommended.
- Bisphosphonates (alendronate): May increase risk for GI ulceration
- Corticosteroids: Concomitant administration significantly increases the risks for GI adverse effects and ulceration
- Furosemide: Naproxen may reduce the saluretic and diuretic effects of furosemide
- Highly protein bound drugs (phenytoin, valproic acid, sulfonamides): Potential displacement leading to increased serum levels and duration of action of the displaced drug
- Methotrexate: Serious toxicity has occurred; use together with extreme caution
- Probenecid: May cause a significant increase in serum levels and half-life of naproxen
常見問題
萘普生用於寵物有什麼用途？
> **危險警告**：絕對不要在沒有獸醫師明確指示的情況下，將人類的非處方止痛藥（如 Aleve®）給予您的寵物。萘普生對狗和貓具有高度毒性。 * 如果您的寵物被處方了萘普生，請嚴格遵守給藥時間表（對狗而言，給藥頻率可能低至每兩天一次）。 * 如果您發現以下情況，**請立即停藥並聯繫您的獸醫師**： * 食慾不振或精神沉鬱 * 嘔吐（特別是含有血液或看起來像咖啡渣的嘔吐物） * 腹瀉或排出黑色柏油狀糞便 * 飲水或排尿習慣改變
萘普生對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。