馬瓦考昔
別名: Trocoxil
> **極度重要：** 這**不是**每天服用的藥物。請嚴格按照獸醫師指示的時程給藥（通常在第1天、第14天給藥後，改為嚴格的每月一次）。請勿自行增加劑量。 * **隨餐服用：** 必須與狗狗一天中最大份量的一餐一起餵食。與食物一起服用能大幅提升藥物在胃部的吸收率。 * **注意副作用：** 若觀察到食慾不振、嘔吐、血便或深色/柏油狀糞便、行為改變，或飲水/排尿習慣改變，請立即聯繫獸醫師。*注意：由於此藥物在體內停留時間很長，副作用可能會在最後一次給藥後的數週才出現。* * **安全存放：** 本咀嚼錠對狗狗具有極佳的適口性。請務必將其存放在所有寵物和兒童絕對無法觸及的地方，以防誤食過量。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Any
- Pain and inflammation associated with degenerative joint disease in dogs aged 12 months or more in cases where continuous treatment exceeding one month is indicated
- Pain and inflammation associated with degenerative joint disease (osteoarthritis)
給藥方式
可能的副作用
- Inappetence
- Diarrhea
- Vomiting
- Depression
- Renal toxicity
- Gastrointestinal ulceration
- Gastrointestinal ulceration or bleeding
- Vomiting and diarrhoea
- Renal toxicity (especially if dehydrated or hypotensive)
- Hepatic accumulation (in poor metabolizers)
- Theoretical risk of precipitating cardiac failure
注意事項與禁忌
- Dogs less than 12 months of age
- Dogs less than 5 kg body weight
- Gastrointestinal disorders including ulceration and bleeding
- Evidence of a hemorrhagic disorder
- Impaired renal or hepatic function
- Cardiac insufficiency
- Hypersensitivity to mavacoxib, sulfonamides, or excipients
- Pregnant, breeding, or lactating animals
- Dehydrated, hypovolemic, or hypotensive animals
- Dehydrated, hypovolaemic, or hypotensive patients
- Gastrointestinal disease or ulceration
- Blood clotting disorders
- Liver disease (prolongs metabolism and causes accumulation)
- Renal disease (requires careful evaluation, generally avoid)
- Pregnant or lactating animals
- Dogs < 12 months of age
- Dogs < 5 kg body weight
- Cats
- Do not use concomitantly with glucocorticoids or other NSAIDs. Do not administer other NSAIDs within 1 month of the last administration of mavacoxib. Avoid use in any dehydrated, hypovolemic, or hypotensive animal, as there is a potential risk of increased renal toxicity. Concurrent administration of potentially nephrotoxic medicinal products should be avoided. Animals should not become dehydrated when receiving this or other NSAIDs.
藥物相互作用
- ACE Inhibitors (e.g., enalapril, benazepril): NSAIDs can reduce effects on blood pressure and potentially reduce renal blood flow, increasing the risk for renal injury.
- Aspirin: May increase the risk of gastrointestinal toxicity (ulceration, bleeding, vomiting, diarrhea). Long washout periods are warranted when switching.
- Corticosteroids (e.g., prednisone): May increase the risk of gastrointestinal toxicity (ulceration, bleeding, vomiting, diarrhea). Concurrent use is contraindicated.
- Digoxin: NSAIDs may increase serum levels of digoxin.
- Fluconazole: May increase plasma levels of mavacoxib (extrapolated from celecoxib data in humans).
- Furosemide: NSAIDs may reduce saluretic and diuretic effects.
- Methotrexate: Serious toxicity has occurred when NSAIDs have been used concomitantly; use together with extreme caution.
- Nephrotoxic Drugs (e.g., aminoglycosides, amphotericin B): May enhance the risk of nephrotoxicity development.
- Other NSAIDs: May increase the risk of gastrointestinal toxicity. Do not administer other NSAIDs within 1 month of the last administration of mavacoxib.
- Glucocorticoids: Increased risk of severe gastrointestinal ulceration and bleeding.
- Aminoglycosides: Increased risk of nephrotoxicity.
- Other nephrotoxic agents: Synergistic risk of acute kidney injury.
常見問題
馬瓦考昔用於寵物有什麼用途？
> 極度重要： 這不是每天服用的藥物。請嚴格按照獸醫師指示的時程給藥（通常在第1天、第14天給藥後，改為嚴格的每月一次）。請勿自行增加劑量。 • 隨餐服用： 必須與狗狗一天中最大份量的一餐一起餵食。與食物一起服用能大幅提升藥物在胃部的吸收率。 • 注意副作用： 若觀察到食慾不振、嘔吐、血便或深色/柏油狀糞便、行為改變，或飲水/排尿習慣改變，請立即聯繫獸醫師。*注意：由於此藥物在體內停留時間很長，副作用可能會在最後一次給藥後的數週才出現。* • 安全存放： 本咀嚼錠對狗狗具有極佳的適口性。請務必將其存放在所有寵物和兒童絕對無法觸及的地方，以防誤食過量。
馬瓦考昔對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。