馬瓦考昔
別名: Trocoxil
藥物類別: Non-Steroidal Anti-Inflammatory Drug (NSAID) - COX-2 Selective
> **極度重要:** 這**不是**每天服用的藥物。請嚴格按照獸醫師指示的時程給藥(通常在第1天、第14天給藥後,改為嚴格的每月一次)。請勿自行增加劑量。 * **隨餐服用:** 必須與狗狗一天中最大份量的一餐一起餵食。與食物一起服用能大幅提升藥物在胃部的吸收率。 * **注意副作用:** 若觀察到食慾不振、嘔吐、血便或深色/柏油狀糞便、行為改變,或飲水/排尿習慣改變,請立即聯繫獸醫師。*注意:由於此藥物在體內停留時間很長,副作用可能會在最後一次給藥後的數週才出現。* * **安全存放:** 本咀嚼錠對狗狗具有極佳的適口性。請務必將其存放在所有寵物和兒童絕對無法觸及的地方,以防誤食過量。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Any
- Pain and inflammation associated with degenerative joint disease in dogs aged 12 months or more in cases where continuous treatment exceeding one month is indicated
- Pain and inflammation associated with degenerative joint disease (osteoarthritis)
給藥方式
PO
可能的副作用
- Inappetence
- Diarrhea
- Vomiting
- Depression
- Renal toxicity
- Gastrointestinal ulceration
- Gastrointestinal ulceration or bleeding
- Vomiting and diarrhoea
- Renal toxicity (especially if dehydrated or hypotensive)
- Hepatic accumulation (in poor metabolizers)
- Theoretical risk of precipitating cardiac failure
注意事項與禁忌
- Dogs less than 12 months of age
- Dogs less than 5 kg body weight
- Gastrointestinal disorders including ulceration and bleeding
- Evidence of a hemorrhagic disorder
- Impaired renal or hepatic function
- Cardiac insufficiency
- Hypersensitivity to mavacoxib, sulfonamides, or excipients
- Pregnant, breeding, or lactating animals
- Dehydrated, hypovolemic, or hypotensive animals
- Dehydrated, hypovolaemic, or hypotensive patients
- Gastrointestinal disease or ulceration
- Blood clotting disorders
- Liver disease (prolongs metabolism and causes accumulation)
藥物相互作用
- ACE Inhibitors (e.g., enalapril, benazepril): NSAIDs can reduce effects on blood pressure and potentially reduce renal blood flow, increasing the risk for renal injury.
- Aspirin: May increase the risk of gastrointestinal toxicity (ulceration, bleeding, vomiting, diarrhea). Long washout periods are warranted when switching.
- Corticosteroids (e.g., prednisone): May increase the risk of gastrointestinal toxicity (ulceration, bleeding, vomiting, diarrhea). Concurrent use is contraindicated.
- Digoxin: NSAIDs may increase serum levels of digoxin.
- Fluconazole: May increase plasma levels of mavacoxib (extrapolated from celecoxib data in humans).
- Furosemide: NSAIDs may reduce saluretic and diuretic effects.
- Methotrexate: Serious toxicity has occurred when NSAIDs have been used concomitantly; use together with extreme caution.
- Nephrotoxic Drugs (e.g., aminoglycosides, amphotericin B): May enhance the risk of nephrotoxicity development.
- Other NSAIDs: May increase the risk of gastrointestinal toxicity. Do not administer other NSAIDs within 1 month of the last administration of mavacoxib.
常見問題
馬瓦考昔用於寵物有什麼用途?
> **極度重要:** 這**不是**每天服用的藥物。請嚴格按照獸醫師指示的時程給藥(通常在第1天、第14天給藥後,改為嚴格的每月一次)。請勿自行增加劑量。 * **隨餐服用:** 必須與狗狗一天中最大份量的一餐一起餵食。與食物一起服用能大幅提升藥物在胃部的吸收率。 * **注意副作用:** 若觀察到食慾不振、嘔吐、血便或深色/柏油狀糞便、行為改變,或飲水/排尿習慣改變,請立即聯繫獸醫師。*注意:由於此藥物在體內停留時間很長,副作用可能會在最後一次給藥後的數週才出現。* * **安全存放:** 本咀嚼錠對狗狗具有極佳的適口性。請務必將其存放在所有寵物和兒童絕對無法觸及的地方,以防誤食過量。
馬瓦考昔對我的寵物安全嗎?
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。