依託咪酯
別名: Amidate, Hypnomidate, Radenarcon, Sibul
藥物類別: Injectable Anesthetic (Non-barbiturate)
依託咪酯是一種強效的鎮靜催眠麻醉劑。 * **僅限專業使用：** 僅限由獸醫專業人員在具備完善病患監測設備（如心電圖、血壓、血氧監測）的臨床環境中使用。 * **使用原因：** 如果您的寵物患有心臟疾病、頭部外傷或屬於重症，獸醫可能會選擇這種特定的麻醉劑，因為它對心血管系統的影響比其他麻醉劑溫和得多。 * **預期情況：** 它用於在手術前安全地引導寵物進入睡眠狀態。由於它本身不具備止痛效果，您的寵物將會根據需要接受額外的止痛藥物。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As an induction agent
- As an induction agent
- As an induction agent
- As an induction agent in the cardiovascular unstable patient
- As an induction agent in the cardiovascular unstable patient (Rabbits)
- As an induction agent
- As an induction agent
- As an induction agent
給藥方式
IV
可能的副作用
- Pain at intravenous injection site
- Myoclonus (skeletal muscle movements)
- Vomiting and post-operative retching
- Eye movements
- Hemolysis (due to propylene glycol carrier)
- Brief hypoventilation and decreased arterial blood pressure
- Apnea, laryngospasm, or hiccups (reported in humans)
注意事項與禁忌
- Known hypersensitivity to etomidate
- Maintenance of anesthesia (due to cumulative adrenal suppression)
- Use as a sole agent for painful procedures (lacks analgesia)
- > **Adrenocortical Suppression:** Etomidate inhibits cortisol production. It should only be used for induction, not maintenance. Use with extreme caution in patients with impaired adrenocortical function. Exogenous glucocorticoids (e.g., dexamethasone) should be considered in severely compromised animals. * **Hepatic/Renal Impairment:** Elimination half-lives may be significantly increased. The propylene glycol carrier may be problematic in patients with liver dysfunction. * **Hemolysis & Pain:** Injecting into a running IV line is recommended to decrease pain on injection and potentially reduce hemolysis caused by the propylene glycol vehicle. * **Premedication:** Administering a benzodiazepine (diazepam, midazolam) or opiate prior to etomidate can minimize myoclonus, vomiting, and potential seizure-like activity.
藥物相互作用
- CNS/Respiratory Depressants (e.g., barbiturates, opiates, anesthetics): Additive pharmacological effects; can increase CNS or respiratory depression.
- Verapamil: Associated with potentiating the anesthetic and respiratory depressant effects of etomidate.
常見問題
依託咪酯用於寵物有什麼用途？
依託咪酯是一種強效的鎮靜催眠麻醉劑。 * **僅限專業使用：** 僅限由獸醫專業人員在具備完善病患監測設備（如心電圖、血壓、血氧監測）的臨床環境中使用。 * **使用原因：** 如果您的寵物患有心臟疾病、頭部外傷或屬於重症，獸醫可能會選擇這種特定的麻醉劑，因為它對心血管系統的影響比其他麻醉劑溫和得多。 * **預期情況：** 它用於在手術前安全地引導寵物進入睡眠狀態。由於它本身不具備止痛效果，您的寵物將會根據需要接受額外的止痛藥物。
依託咪酯對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。