Etomidate
別名: Amidate, Hypnomidate, Radenarcon, Sibul
Etomidate is a potent sedative-hypnotic anesthetic agent. * **Professional Use Only:** It is used strictly by veterinary professionals in a clinical setting where adequate patient monitoring (ECG, blood pressure, oxygenation) is available. * **Why it is used:** Your veterinarian may choose this specific anesthetic if your pet has a preexisting heart condition, head trauma, or is critically ill, because etomidate is very gentle on the cardiovascular system compared to other anesthetics. * **What to expect:** It is used to safely induce sleep before a procedure. Because it does not provide pain relief on its own, your pet will receive additional pain medications as needed.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As an induction agent
- As an induction agent
- As an induction agent
- As an induction agent in the cardiovascular unstable patient
- As an induction agent in the cardiovascular unstable patient (Rabbits)
- As an induction agent
- As an induction agent
- As an induction agent
給藥方式
可能的副作用
- Pain at intravenous injection site
- Myoclonus (skeletal muscle movements)
- Vomiting and post-operative retching
- Eye movements
- Hemolysis (due to propylene glycol carrier)
- Brief hypoventilation and decreased arterial blood pressure
- Apnea, laryngospasm, or hiccups (reported in humans)
注意事項與禁忌
- Known hypersensitivity to etomidate
- Maintenance of anesthesia (due to cumulative adrenal suppression)
- Use as a sole agent for painful procedures (lacks analgesia)
- > **Adrenocortical Suppression:** Etomidate inhibits cortisol production. It should only be used for induction, not maintenance. Use with extreme caution in patients with impaired adrenocortical function. Exogenous glucocorticoids (e.g., dexamethasone) should be considered in severely compromised animals. * **Hepatic/Renal Impairment:** Elimination half-lives may be significantly increased. The propylene glycol carrier may be problematic in patients with liver dysfunction. * **Hemolysis & Pain:** Injecting into a running IV line is recommended to decrease pain on injection and potentially reduce hemolysis caused by the propylene glycol vehicle. * **Premedication:** Administering a benzodiazepine (diazepam, midazolam) or opiate prior to etomidate can minimize myoclonus, vomiting, and potential seizure-like activity.
藥物相互作用
- CNS/Respiratory Depressants (e.g., barbiturates, opiates, anesthetics): Additive pharmacological effects; can increase CNS or respiratory depression.
- Verapamil: Associated with potentiating the anesthetic and respiratory depressant effects of etomidate.
常見問題
Etomidate用於寵物有甚麼用途？
Etomidate is a potent sedative-hypnotic anesthetic agent. * **Professional Use Only:** It is used strictly by veterinary professionals in a clinical setting where adequate patient monitoring (ECG, blood pressure, oxygenation) is available. * **Why it is used:** Your veterinarian may choose this specific anesthetic if your pet has a preexisting heart condition, head trauma, or is critically ill, because etomidate is very gentle on the cardiovascular system compared to other anesthetics. * **What to expect:** It is used to safely induce sleep before a procedure. Because it does not provide pain relief on its own, your pet will receive additional pain medications as needed.
Etomidate對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。