氯法齊明
別名: Lamprene, Clofozine, Hansepran, Lamcoin, Lampren
藥物類別: Antimycobacterial Antibiotic
**給藥方式:** * 除非獸醫另有指示,否則請**隨餐給予**此藥物,以增加吸收並減少腸胃不適。 **重要警告:** > **變色反應:** 此藥物是一種染料。它很可能會使您寵物的皮膚變色(通常是粉紅色,但也可能從紅色、橘色到棕色不等)。它還可能導致眼淚、尿液、糞便和其他體液變成棕黑色。 * 這種變色是藥物正常且預期的反應,並無害處,但可能會弄髒布料,並且在治療結束後可能持續數月才會消退。 **治療療程:** * 分枝桿菌感染的治療時間非常長(通常需要數月)。即使您的寵物看起來已經好轉,除非獸醫指示,否則請勿提早停藥。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Avian mycobacteriosis
- Avian mycobacteriosis (recommended regime for raptors)
- Mycobacterium avium complex (MAC) as part of a multi-drug regimen
- M. avium intracellularae complex infections, leprosy, or opportunistic mycobacteriosis
- Mycobacterial infections
- Treatment of feline leprosy
- Treatment of localized atypical mycobacterial infections
- M. avium intracellularae complex infections, leprosy or opportunistic mycobacteriosis
- Mycobacterial infections (including feline leprosy)
給藥方式
PO
可能的副作用
- Skin, eye, and body fluid discoloration (pink to brownish-black)
- Gastrointestinal pain, nausea, vomiting, diarrhea (dose-limiting)
- Hepatotoxicity (reported in a dog receiving concurrent rifampin)
- Photosensitization (reported in a cat)
- Nausea
- Diarrhoea
- Discoloration of skin, eyes, and body fluids (red-brown/orange)
- Renal impairment
- Hepatic impairment
- Photosensitization
注意事項與禁忌
- Use with caution in patients with pre-existing gastrointestinal conditions (diarrhea, abdominal pain)
- Known hypersensitivity to clofazimine
- Use with caution in patients with pre-existing gastrointestinal conditions such as diarrhea or abdominal pain. The drug is highly lipophilic and has an extremely long half-life, meaning adverse effects (like skin discoloration) can persist for months to years after discontinuation. It may be difficult to obtain and accurately dose for small animals.
藥物相互作用
- Isoniazid: May reduce clofazimine levels in the skin and increase amounts in plasma and urine; clinical significance is unclear.
- Dapsone: May reduce the anti-inflammatory effects of clofazimine; clinical significance is unclear.
常見問題
氯法齊明用於寵物有什麼用途?
**給藥方式:** * 除非獸醫另有指示,否則請**隨餐給予**此藥物,以增加吸收並減少腸胃不適。 **重要警告:** > **變色反應:** 此藥物是一種染料。它很可能會使您寵物的皮膚變色(通常是粉紅色,但也可能從紅色、橘色到棕色不等)。它還可能導致眼淚、尿液、糞便和其他體液變成棕黑色。 * 這種變色是藥物正常且預期的反應,並無害處,但可能會弄髒布料,並且在治療結束後可能持續數月才會消退。 **治療療程:** * 分枝桿菌感染的治療時間非常長(通常需要數月)。即使您的寵物看起來已經好轉,除非獸醫指示,否則請勿提早停藥。
氯法齊明對我的寵物安全嗎?
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。