絨毛膜促性腺激素 (HCG)

用途

• HCG Challenge test (Male cats or females with suspected sexual differentiation disorder)
• HCG Challenge test (Queens to diagnose functional ovarian tissue)
• Infertility, reduced libido, testis descent in male cats
• Infertility in queens due to confirmed ovulation failure
• To induce ovulation in anestrus queens
• After artificial insemination
• Estrus management
• Treatment of ovarian cysts
• Cryptorchidism (Foals)
• To induce ovulation in early estrus (dominant follicle >35 mm)
• Treatment of persistent follicles during the early transition period
• To hasten ovulation and reduce variability of estrus after prostaglandin synchronization

給藥方式

可能的副作用

• Hypersensitivity reactions / Anaphylaxis
• Pain at the injection site
• Antibody production leading to diminished efficacy (with repeated use)
• Abortion in mares if given prior to the 35th day of pregnancy
• Gynecomastia, headache, depression, irritability, and edema (reported in humans)

注意事項與禁忌

• Androgen-dependent neoplasias (e.g., prostatic carcinoma)
• Precocious puberty
• Known hypersensitivity to HCG
• Pregnancy (FDA Category X in humans, unless specifically indicated for reproductive management)
• > **Warning:** Antibody production to this hormone has been reported after repetitive use, resulting in diminished effect. * **Pregnancy:** FDA Category X in humans (risk of use clearly outweighs any possible benefit). May cause abortion in mares prior to the 35th day of pregnancy due to increased estrogen levels. * **Administration:** Must be given parenterally; it is destroyed in the GI tract if given orally.

常見問題