頭孢替坦
別名: Cefotan, Apacef, Apatef, Ceftenon, Cepan, Darvilen, Yamatetan
藥物類別: 2nd Generation Cephalosporin (Cephamycin)
頭孢替坦是一種注射型抗生素，通常由獸醫師在醫院內給予，用於治療嚴重的細菌感染。 - **副作用**：本藥物通常耐受性極佳。但請注意是否有腸胃不適、腹瀉或異常出血/瘀斑的跡象。 - **過敏反應**：如果您的寵物曾對青黴素或其他頭孢菌素類抗生素有過敏反應，請立即告知您的獸醫師。 - **哺乳期**：如果您的寵物正在懷孕或哺乳，請告知獸醫師，因為藥物可能會進入乳汁，並可能導致哺乳幼犬/貓出現輕微腹瀉。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Sepsis
- Susceptible infections
- Soft tissue infections
- Bacteremia, sepsis
給藥方式
IVIMSC
可能的副作用
- Pain at IM injection site
- Thrombophlebitis (IV administration)
- Hypersensitivity reactions (rash, fever, anaphylaxis)
- Bleeding tendencies (hypoprothrombinemia due to NMTT side chain)
- Gastrointestinal flora alteration (diarrhea, superinfections)
- Rarely: nephrotoxicity, neurotoxicity, neutropenia, thrombocytopenia at high doses
注意事項與禁忌
- Known hypersensitivity to cephamycins or cephalosporins
- Caution in patients with documented hypersensitivity to penicillins or other beta-lactams (cross-reactivity possible)
- Caution in patients with severe renal dysfunction (dose interval adjustment may be required)
- > **Cross-Reactivity:** Use cautiously in patients with known penicillin allergies due to a 1-15% chance of cross-reactivity. > **Renal Impairment:** Elimination half-lives may be significantly prolonged in patients with severely diminished renal function; dosing intervals may need to be extended. > **Laboratory Interference:** May cause false-positive urine glucose tests (cupric sulfate method) and falsely elevated serum/urine creatinine (Jaffe reaction). Can also cause a false-positive direct Coombs' test.
藥物相互作用
- Alcohol: Potential for a disulfiram-like reaction (vomiting, etc.) due to the NMTT side chain.
- Aminoglycosides: Potential additive nephrotoxicity; do not mix together in the same syringe/fluid bag (administer separately). May have synergistic antibacterial activity.
- Nephrotoxic drugs (e.g., Amphotericin B): Potential additive nephrotoxicity.
常見問題
頭孢替坦用於寵物有什麼用途？
頭孢替坦是一種注射型抗生素，通常由獸醫師在醫院內給予，用於治療嚴重的細菌感染。 - 副作用：本藥物通常耐受性極佳。但請注意是否有腸胃不適、腹瀉或異常出血/瘀斑的跡象。 - 過敏反應：如果您的寵物曾對青黴素或其他頭孢菌素類抗生素有過敏反應，請立即告知您的獸醫師。 - 哺乳期：如果您的寵物正在懷孕或哺乳，請告知獸醫師，因為藥物可能會進入乳汁，並可能導致哺乳幼犬/貓出現輕微腹瀉。
頭孢替坦對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。