Cefotetan
別名: Cefotan, Apacef, Apatef, Ceftenon, Cepan, Darvilen, Yamatetan
Cefotetan is an injectable antibiotic typically administered by your veterinarian in a hospital setting to treat serious bacterial infections. - **Side Effects:** It is generally very well tolerated. However, watch for signs of stomach upset, diarrhea, or unusual bleeding/bruising. - **Allergies:** Inform your veterinarian immediately if your pet has ever had an allergic reaction to penicillin or other cephalosporin antibiotics. - **Nursing:** Let your veterinarian know if your pet is pregnant or nursing, as the drug can pass into milk and potentially cause mild diarrhea in nursing offspring.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Sepsis
- Susceptible infections
- Soft tissue infections
- Bacteremia, sepsis
給藥方式
可能的副作用
- Pain at IM injection site
- Thrombophlebitis (IV administration)
- Hypersensitivity reactions (rash, fever, anaphylaxis)
- Bleeding tendencies (hypoprothrombinemia due to NMTT side chain)
- Gastrointestinal flora alteration (diarrhea, superinfections)
- Rarely: nephrotoxicity, neurotoxicity, neutropenia, thrombocytopenia at high doses
注意事項與禁忌
- Known hypersensitivity to cephamycins or cephalosporins
- Caution in patients with documented hypersensitivity to penicillins or other beta-lactams (cross-reactivity possible)
- Caution in patients with severe renal dysfunction (dose interval adjustment may be required)
- > **Cross-Reactivity:** Use cautiously in patients with known penicillin allergies due to a 1-15% chance of cross-reactivity. > **Renal Impairment:** Elimination half-lives may be significantly prolonged in patients with severely diminished renal function; dosing intervals may need to be extended. > **Laboratory Interference:** May cause false-positive urine glucose tests (cupric sulfate method) and falsely elevated serum/urine creatinine (Jaffe reaction). Can also cause a false-positive direct Coombs' test.
藥物相互作用
- Alcohol: Potential for a disulfiram-like reaction (vomiting, etc.) due to the NMTT side chain.
- Aminoglycosides: Potential additive nephrotoxicity; do not mix together in the same syringe/fluid bag (administer separately). May have synergistic antibacterial activity.
- Nephrotoxic drugs (e.g., Amphotericin B): Potential additive nephrotoxicity.
常見問題
Cefotetan用於寵物有甚麼用途？
Cefotetan is an injectable antibiotic typically administered by your veterinarian in a hospital setting to treat serious bacterial infections. - **Side Effects:** It is generally very well tolerated. However, watch for signs of stomach upset, diarrhea, or unusual bleeding/bruising. - **Allergies:** Inform your veterinarian immediately if your pet has ever had an allergic reaction to penicillin or other cephalosporin antibiotics. - **Nursing:** Let your veterinarian know if your pet is pregnant or nursing, as the drug can pass into milk and potentially cause mild diarrhea in nursing offspring.
Cefotetan對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。