Cefotetan
別名: Cefotan, Apacef, Apatef, Ceftenon, Cepan, Darvilen, Yamatetan
Cefotetan is an injectable antibiotic typically administered by your veterinarian in a hospital setting to treat serious bacterial infections. - **Side Effects:** It is generally very well tolerated. However, watch for signs of stomach upset, diarrhea, or unusual bleeding/bruising. - **Allergies:** Inform your veterinarian immediately if your pet has ever had an allergic reaction to penicillin or other cephalosporin antibiotics. - **Nursing:** Let your veterinarian know if your pet is pregnant or nursing, as the drug can pass into milk and potentially cause mild diarrhea in nursing offspring.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Sepsis
- Susceptible infections
- Soft tissue infections
- Bacteremia, sepsis
給藥方式
可能的副作用
- Pain at IM injection site
- Thrombophlebitis (IV administration)
- Hypersensitivity reactions (rash, fever, anaphylaxis)
- Bleeding tendencies (hypoprothrombinemia due to NMTT side chain)
- Gastrointestinal flora alteration (diarrhea, superinfections)
- Rarely: nephrotoxicity, neurotoxicity, neutropenia, thrombocytopenia at high doses
注意事項與禁忌
- Known hypersensitivity to cephamycins or cephalosporins
- Caution in patients with documented hypersensitivity to penicillins or other beta-lactams (cross-reactivity possible)
- Caution in patients with severe renal dysfunction (dose interval adjustment may be required)
- > **Cross-Reactivity:** Use cautiously in patients with known penicillin allergies due to a 1-15% chance of cross-reactivity. > **Renal Impairment:** Elimination half-lives may be significantly prolonged in patients with severely diminished renal function; dosing intervals may need to be extended. > **Laboratory Interference:** May cause false-positive urine glucose tests (cupric sulfate method) and falsely elevated serum/urine creatinine (Jaffe reaction). Can also cause a false-positive direct Coombs' test.
藥物相互作用
- Alcohol: Potential for a disulfiram-like reaction (vomiting, etc.) due to the NMTT side chain.
- Aminoglycosides: Potential additive nephrotoxicity; do not mix together in the same syringe/fluid bag (administer separately). May have synergistic antibacterial activity.
- Nephrotoxic drugs (e.g., Amphotericin B): Potential additive nephrotoxicity.
常見問題
Cefotetan用於寵物有甚麼用途？
Cefotetan is an injectable antibiotic typically administered by your veterinarian in a hospital setting to treat serious bacterial infections. - **Side Effects:** It is generally very well tolerated. However, watch for signs of stomach upset, diarrhea, or unusual bleeding/bruising. - **Allergies:** Inform your veterinarian immediately if your pet has ever had an allergic reaction to penicillin or other cephalosporin antibiotics. - **Nursing:** Let your veterinarian know if your pet is pregnant or nursing, as the drug can pass into milk and potentially cause mild diarrhea in nursing offspring.
Cefotetan對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。