阿米卡星硫酸鹽
別名: Amikin, Amiglyde-V
藥物類別: Antibiotic - Aminoglycoside
阿米卡星是一種用於治療嚴重感染的強效抗生素。因為它是注射給藥,如果您在家中為寵物治療,獸醫會指導您如何操作。 > **重要提示:** 該藥物可能對腎臟和內耳(影響聽力和平衡)造成損害。 - **保持水分至關重要:** 確保您的寵物隨時有充足的新鮮飲水,以幫助保護牠們的腎臟。 - **密切觀察:** 如果您發現寵物的飲水或排尿習慣改變(喝多/尿多或減少)、失去平衡、頭部傾斜或明顯聽力下降,請立即聯繫獸醫。 - 除非獸醫明確指示,否則請勿將此藥物與其他藥物混合在同一注射器中。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Empiric therapy
- Susceptible infections
- Sepsis
- Susceptible infections
- Susceptible infections
- Susceptible infections
- Susceptible infections
- Susceptible infections
- Susceptible infections (Neonatal foals)
- Susceptible infections (Neonatal foals)
- Susceptible infections (Adults)
- Susceptible infections (Foals <30 days old)
- Septic joints
- Uterine infusion
給藥方式
IVIMSCIntrauterineIntra-articularRegional intravenous limb perfusion (RILP)
可能的副作用
- Nephrotoxicity (tubular necrosis)
- Ototoxicity (auditory and vestibular)
- Neuromuscular blockade
- Facial edema
- Injection site pain/inflammation
- Peripheral neuropathy
- Hypersensitivity reactions
注意事項與禁忌
- Hypersensitivity to aminoglycosides
- Generally contraindicated in rabbits/hares (adversely affects GI flora balance)
- Use with extreme caution in patients with preexisting **renal disease**; requires concomitant monitoring and dosage interval adjustments. Other risk factors for toxicity include age (neonatal and geriatric), fever, sepsis, and dehydration. - **Ototoxicity:** Can cause irreversible ototoxicity; use with caution in 'working' dogs (e.g., seeing-eye, herding, hearing-impaired assistance dogs). - **Neuromuscular Disorders:** Use with caution in patients with conditions like myasthenia gravis due to neuromuscular blocking activity. - **Breed Considerations:** Sighthound dogs (e.g., Greyhounds) have significantly smaller volumes of distribution and may require reduced dosages. - **Food Animals:** Use in food-producing animals is controversial as drug residues may persist for long periods, particularly in renal tissue.
藥物相互作用
- Beta-lactam antibiotics (penicillins, cephalosporins): May have synergistic effects against some bacteria; potential for physical inactivation of aminoglycosides in vitro (do not mix together) and in vivo (patients in renal failure).
- Cephalosporins: Potentially could cause additive nephrotoxicity (controversial, well documented only with older agents like cephaloridine and cephalothin).
- Loop or Osmotic Diuretics (e.g., furosemide, torsemide, mannitol): Concurrent use may increase the nephrotoxic or ototoxic potential of the aminoglycosides.
- NSAIDs: May cause nephrotoxic effects; concurrent use with aminoglycosides should generally be avoided.
- Other Nephrotoxic Drugs (e.g., cisplatin, amphotericin B, polymyxin B, vancomycin): Potential for increased risk for nephrotoxicity.
- Neuromuscular blocking agents & General anesthetics: Concomitant use could potentiate neuromuscular blockade.
常見問題
阿米卡星硫酸鹽用於寵物有什麼用途?
阿米卡星是一種用於治療嚴重感染的強效抗生素。因為它是注射給藥,如果您在家中為寵物治療,獸醫會指導您如何操作。 > **重要提示:** 該藥物可能對腎臟和內耳(影響聽力和平衡)造成損害。 - **保持水分至關重要:** 確保您的寵物隨時有充足的新鮮飲水,以幫助保護牠們的腎臟。 - **密切觀察:** 如果您發現寵物的飲水或排尿習慣改變(喝多/尿多或減少)、失去平衡、頭部傾斜或明顯聽力下降,請立即聯繫獸醫。 - 除非獸醫明確指示,否則請勿將此藥物與其他藥物混合在同一注射器中。
阿米卡星硫酸鹽對我的寵物安全嗎?
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。