乙醯甘露聚糖

用途

• Aid in treatment and management of fibrosarcoma
• Aid in treatment and management of fibrosarcoma

給藥方式

可能的副作用

• Hypersensitivity reactions
• Localized necrosis at injection sites
• Hyperactivity
• Lethargy
• Fever
• Hypotension
• Salivation (with IV bolus)
• Weakness and collapse (with IV bolus)
• Tachycardia and tachypnea (with IV bolus)
• Prolonged pain or bleeding at intralesional injection sites
• Monocyte infiltrates on peritoneal surfaces, liver, lung, and spleen (with IP injection)
• Abdominal pain, diarrhea, and vomiting (with high-dose IP injection)

注意事項與禁忌

• Patients with demonstrated past severe hypersensitivity reactions to acemannan
• > **Important Warning:** Bolus IV administration can cause severe systemic reactions including salivation, weakness, collapse, hypotension, tachycardia, and tachypnea. * **Intraperitoneal (IP) Use:** Can cause monocyte infiltrates on peritoneal surfaces and abdominal organs, potentially leading to abdominal pain, vomiting, and diarrhea at high doses. * **Pregnancy/Nursing:** Safety has not been established in pregnant or nursing animals, though its chemical nature suggests it is unlikely to be a teratogen.

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