Ursodiol
別名: Actigall, URSO 250, URSO Forte
* **Give with food:** Ursodiol dissolves more rapidly in the presence of bile or pancreatic juice, so it is best administered with a meal. * **Patience is key:** Liver disease management is often a long-term process. Do not stop the medication without consulting your veterinarian. * **Monitor for side effects:** While generally very safe, watch for signs of diarrhea or gastrointestinal upset and report them to your veterinarian.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Cholestatic liver disease, cholangitis/cholangiohepatitis, chronic hepatitis, and copper-associated hepatopathy
- Chronic active hepatitis, fibrosis, and cirrhosis
- Adjunctive treatment of chronic hepatitis
- Adjunctive treatment of liver disease
- Adjunctive treatment of chronic hepatitis
- Cholestatic liver disease, cholangitis/cholangiohepatitis, chronic hepatitis, and copper-associated hepatopathy
- Chronic active hepatitis, fibrosis and cirrhosis
給藥方式
可能的副作用
- Diarrhea
- Gastrointestinal upset (rare)
注意事項與禁忌
- Rabbits and other hindgut fermenters (converted to toxic lithocholic acid)
- Biliary obstruction
- Biliary fistulas
- Cholecystitis
- Pancreatitis
- Cholangitis (if complete obstruction is present)
- Ursodiol is strictly contraindicated in rabbits and hindgut fermenters. Use with caution in patients with complications associated with gallstones (e.g., biliary obstruction, cholecystitis). While useful for chronic liver disease, some patients may experience further impairment of bile acid metabolism. It will not dissolve calcified radiopaque stones or radiolucent bile pigment stones.
藥物相互作用
- Aluminum-containing antacids: May bind to ursodiol, thereby reducing its efficacy
- Cholestyramine resin: May bind to ursodiol, thereby reducing its efficacy
- Taurine: Theoretical concern that chronic administration in cats may lead to taurine deficiency
常見問題
Ursodiol用於寵物有甚麼用途？
* **Give with food:** Ursodiol dissolves more rapidly in the presence of bile or pancreatic juice, so it is best administered with a meal. * **Patience is key:** Liver disease management is often a long-term process. Do not stop the medication without consulting your veterinarian. * **Monitor for side effects:** While generally very safe, watch for signs of diarrhea or gastrointestinal upset and report them to your veterinarian.
Ursodiol對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。