Trimeprazine with Prednisolone
別名: Temaril-P, Vanectyl-P
- **Increased Thirst and Urination**: Your dog will likely drink more water and need to urinate more frequently. Ensure they have constant access to fresh water and provide extra bathroom breaks. - **Increased Appetite**: This medication can make your dog very hungry. Stick to their normal feeding schedule to prevent unwanted weight gain. - **Sedation**: You may notice mild drowsiness or lethargy, especially during the first few days of treatment. This is normal but contact your vet if it seems severe. - **Do Not Stop Abruptly**: If your dog has been on this medication for more than a few weeks, the dose must be tapered slowly under veterinary guidance. Stopping suddenly can cause a life-threatening hormonal imbalance. - **Monitor for Infections**: Because this drug suppresses the immune system, contact your veterinarian if you notice signs of infection, worsening skin lesions, or severe lethargy.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Antipruritic and antitussive therapy
- Treatment of pruritus
- Atopic dermatitis
給藥方式
可能的副作用
- Sedation
- Depression
- Hypotension
- Extrapyramidal reactions (rigidity, tremors, weakness, restlessness)
- Polyuria (increased urination)
- Polydipsia (increased thirst)
- Polyphagia (increased appetite)
- Elevated liver enzymes
- Weight loss or weight gain
- Vomiting
- Diarrhea
- Iatrogenic hyperadrenocorticism (Cushing's syndrome) with chronic use
- Delayed wound healing
- Osteoporosis
注意事項與禁忌
- Systemic fungal infections
- Hypovolemia or shock
- Tetanus or strychnine intoxication
- Late pregnancy (last trimester) due to risk of inducing parturition
- Use with caution in patients with hepatic dysfunction, cardiac disease, active bacterial or viral infections, peptic ulcers, acute psychoses, corneal ulcers, Cushingoid syndrome, diabetes, osteoporosis, predisposition to thrombophlebitis, hypertension, congestive heart failure (CHF), renal insufficiency, general debilitation, and in very young animals. If used chronically, therapy must be withdrawn gradually to prevent Addisonian crisis. May alter thyroid testing and skin allergy testing.
藥物相互作用
- ACE Inhibitors: Phenothiazines may increase hypotensive effects
- Amphotericin B: Concomitant use with glucocorticoids may cause severe hypokalemia
- Antacids: May cause reduced GI absorption of oral phenothiazines
- Antidiarrheal mixtures (Kaolin/pectin, bismuth): May cause reduced GI absorption of oral phenothiazines
- Anticholinesterase agents (pyridostigmine, neostigmine): In myasthenia gravis patients, concomitant use may lead to profound muscle weakness
- Aspirin (salicylates): Glucocorticoids may reduce salicylate blood levels
- Cisapride: Increased risk for cardiac arrhythmias when used with phenothiazines
- CNS Depressants (barbiturates, narcotics, anesthetics): May cause additive CNS depression
- Cyclophosphamide: Glucocorticoids may inhibit hepatic metabolism of cyclophosphamide
- Cyclosporine: May mutually inhibit hepatic metabolism, increasing blood levels of both drugs
- Digoxin: Increased risk for arrhythmias secondary to glucocorticoid-induced hypokalemia
常見問題
Trimeprazine with Prednisolone用於寵物有甚麼用途？
- **Increased Thirst and Urination**: Your dog will likely drink more water and need to urinate more frequently. Ensure they have constant access to fresh water and provide extra bathroom breaks. - **Increased Appetite**: This medication can make your dog very hungry. Stick to their normal feeding schedule to prevent unwanted weight gain. - **Sedation**: You may notice mild drowsiness or lethargy, especially during the first few days of treatment. This is normal but contact your vet if it seems severe. - **Do Not Stop Abruptly**: If your dog has been on this medication for more than a few weeks, the dose must be tapered slowly under veterinary guidance. Stopping suddenly can cause a life-threatening hormonal imbalance. - **Monitor for Infections**: Because this drug suppresses the immune system, contact your veterinarian if you notice signs of infection, worsening skin lesions, or severe lethargy.
Trimeprazine with Prednisolone對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。