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繁體中文香港

特美帕嗪與潑尼松龍

別名: Temaril-P, Vanectyl-P

藥物類別: Phenothiazine Antihistamine & Corticosteroid

- **口渴與排尿增加**:您的狗狗可能會喝更多的水,並且需要更頻繁地排尿。請確保牠們隨時有乾淨的飲水,並增加帶牠們外出的次數。 - **食慾增加**:這種藥物會讓狗狗變得非常飢餓。請堅持正常的餵食計畫,以防止不必要的體重增加。 - **鎮靜作用**:在治療的最初幾天,您可能會注意到狗狗有輕微的嗜睡或精神不振。這是正常現象,但如果情況嚴重請聯繫獸醫。 - **請勿突然停藥**:如果您的狗狗已經服用此藥超過幾週,必須在獸醫的指導下緩慢減少劑量。突然停藥可能會導致危及生命的荷爾蒙失調。 - **監測感染跡象**:因為此藥物會抑制免疫系統,如果您發現感染跡象、皮膚病變惡化或嚴重的精神不振,請立即聯繫您的獸醫。

劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。

Veterinary professional? See the full dosing-by-species reference on VetSheet →

用途

  • Antipruritic and antitussive therapy
  • Treatment of pruritus
  • Atopic dermatitis

給藥方式

PO

可能的副作用

  • Sedation
  • Depression
  • Hypotension
  • Extrapyramidal reactions (rigidity, tremors, weakness, restlessness)
  • Polyuria (increased urination)
  • Polydipsia (increased thirst)
  • Polyphagia (increased appetite)
  • Elevated liver enzymes
  • Weight loss or weight gain
  • Vomiting
  • Diarrhea
  • Iatrogenic hyperadrenocorticism (Cushing's syndrome) with chronic use
  • Delayed wound healing
  • Osteoporosis
  • Increased susceptibility to infections

注意事項與禁忌

  • Systemic fungal infections
  • Hypovolemia or shock
  • Tetanus or strychnine intoxication
  • Late pregnancy (last trimester) due to risk of inducing parturition
  • Use with caution in patients with hepatic dysfunction, cardiac disease, active bacterial or viral infections, peptic ulcers, acute psychoses, corneal ulcers, Cushingoid syndrome, diabetes, osteoporosis, predisposition to thrombophlebitis, hypertension, congestive heart failure (CHF), renal insufficiency, general debilitation, and in very young animals. If used chronically, therapy must be withdrawn gradually to prevent Addisonian crisis. May alter thyroid testing and skin allergy testing.

藥物相互作用

  • ACE Inhibitors: Phenothiazines may increase hypotensive effects
  • Amphotericin B: Concomitant use with glucocorticoids may cause severe hypokalemia
  • Antacids: May cause reduced GI absorption of oral phenothiazines
  • Antidiarrheal mixtures (Kaolin/pectin, bismuth): May cause reduced GI absorption of oral phenothiazines
  • Anticholinesterase agents (pyridostigmine, neostigmine): In myasthenia gravis patients, concomitant use may lead to profound muscle weakness
  • Aspirin (salicylates): Glucocorticoids may reduce salicylate blood levels
  • Cisapride: Increased risk for cardiac arrhythmias when used with phenothiazines
  • CNS Depressants (barbiturates, narcotics, anesthetics): May cause additive CNS depression
  • Cyclophosphamide: Glucocorticoids may inhibit hepatic metabolism of cyclophosphamide
  • Cyclosporine: May mutually inhibit hepatic metabolism, increasing blood levels of both drugs
  • Digoxin: Increased risk for arrhythmias secondary to glucocorticoid-induced hypokalemia
  • Diuretics, potassium-depleting (furosemide, thiazides): Concomitant use with glucocorticoids may cause hypokalemia
  • Ephedrine: May increase metabolism of glucocorticoids
  • Estrogens: May potentiate the effects of glucocorticoids
  • Insulin: Insulin requirements may increase due to glucocorticoid-induced hyperglycemia
  • Ketoconazole: May decrease metabolism of glucocorticoids
  • Mitotane: May alter steroid metabolism; higher steroid doses may be needed
  • NSAIDs: Increased risk of gastrointestinal ulceration
  • Vaccines (live attenuated): Virus replication may be augmented; diminished immune response may occur
  • Paroxetine: May increase phenothiazine plasma levels
  • Phenobarbital: May increase the metabolism of glucocorticoids
  • Phenytoin: May increase the metabolism of glucocorticoids
  • Rifampin: May increase the metabolism of glucocorticoids

常見問題

特美帕嗪與潑尼松龍用於寵物有甚麼用途?

- 口渴與排尿增加:您的狗狗可能會喝更多的水,並且需要更頻繁地排尿。請確保牠們隨時有乾淨的飲水,並增加帶牠們外出的次數。 - 食慾增加:這種藥物會讓狗狗變得非常飢餓。請堅持正常的餵食計畫,以防止不必要的體重增加。 - 鎮靜作用:在治療的最初幾天,您可能會注意到狗狗有輕微的嗜睡或精神不振。這是正常現象,但如果情況嚴重請聯繫獸醫。 - 請勿突然停藥:如果您的狗狗已經服用此藥超過幾週,必須在獸醫的指導下緩慢減少劑量。突然停藥可能會導致危及生命的荷爾蒙失調。 - 監測感染跡象:因為此藥物會抑制免疫系統,如果您發現感染跡象、皮膚病變惡化或嚴重的精神不振,請立即聯繫您的獸醫。

特美帕嗪與潑尼松龍對我的寵物安全嗎?

劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。

本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。

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