托芬那酸
別名: Tolfedine, Tolfejec
托芬那酸是一種用於緩解寵物疼痛和發炎的藥物。 **重要給藥指引：** * **遵守給藥時間表：** 如果您的獸醫師開立了每週的給藥計畫（例如，連續給藥 3 到 5 天，然後在一週的剩餘時間停藥），**務必**嚴格遵守。這種「脈衝式」給藥計畫有助於預防嚴重的副作用。 * **與食物一起餵食：** 將此藥物與食物一起餵食可以幫助您的寵物更好地吸收，並可能減少腸胃不適。 * **注意事項：** 如果您的寵物出現嘔吐、腹瀉、食慾不振、飲水量或排尿量增加，或者您發現深色柏油狀糞便（這可能是胃出血的跡象），請立即停藥並聯絡您的獸醫師。 * **請勿混合用藥：** 在寵物服用托芬那酸期間，絕對不要給予人類的止痛藥（如阿斯匹靈或布洛芬）或其他獸醫用 NSAID，因為這可能會導致致命的胃潰瘍或腎衰竭。
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Acute pain
- Pain/inflammation
- Inflammation, pain, and fever
- Inflammation, pain, and fever
- Metritis-mastitis-agalactia (MMA)
- Pneumonia
- Mastitis
- Acute pain
- Chronic pain
- Pain/inflammation
- Inflammation, pain, and fever
- Inflammation, pain, and chronic locomotor disease
給藥方式
可能的副作用
- Vomiting
- Diarrhea
- Gastrointestinal ulceration (at high doses)
- Platelet dysfunction/prolonged bleeding time
- Potential nephrotoxicity (especially in dehydrated patients)
- Gastrointestinal signs (vomiting, diarrhea, anorexia)
- Gastrointestinal ulceration and bleeding
- Renal toxicity (especially during hypotension)
- Potential precipitation of cardiac failure (rare/unknown risk in animals)
注意事項與禁忌
- Hypersensitivity to tolfenamic acid or other fenamates (e.g., meclofenamic acid)
- Active gastrointestinal bleeding or ulceration
- Pre-surgical administration (due to anti-thromboxane/platelet effects)
- Dehydrated, hypovolemic, or hypotensive patients
- Patients with gastrointestinal disease
- Patients with blood clotting problems
- Pregnant animals
- Animals under 6 weeks of age
- Intramuscular (IM) administration in cats
- Use with extreme caution in patients with **decreased renal or hepatic function**. Ensure patients are well-hydrated to mitigate nephrotoxic risks. Like other NSAIDs, tolfenamic acid should be used with caution during pregnancy. Do not use pre-surgically due to its effects on platelet function.
藥物相互作用
- Aspirin: May increase the risk of gastrointestinal toxicity (e.g., ulceration, bleeding, vomiting, diarrhea).
- Corticosteroids: Concomitant therapy may increase the occurrence of gastric ulceration; avoid concurrent use.
- Digoxin: NSAIDs may increase serum levels of digoxin.
- Fluconazole: May increase plasma levels of NSAIDs; potentially affects tolfenamic acid levels in dogs.
- Furosemide: NSAIDs may reduce the saluretic and diuretic effects of furosemide.
- Methotrexate: Serious toxicity has occurred with concomitant NSAID use; use together with extreme caution.
- Nephrotoxic Drugs (e.g., aminoglycosides, amphotericin B): May enhance the risk of nephrotoxicity.
- Other NSAIDs: May increase the risk of gastrointestinal toxicity (e.g., ulceration, bleeding, vomiting, diarrhea).
- Warfarin: Tolfenamic acid is 98-99% protein-bound; may displace highly protein-bound drugs like warfarin, increasing bleeding risk. Monitor closely.
- Glucocorticoids: Increased risk of gastrointestinal ulceration and bleeding. Do not administer concurrently or within 24 hours.
- Aminoglycosides: Increased risk of nephrotoxicity.
常見問題
托芬那酸用於寵物有甚麼用途？
托芬那酸是一種用於緩解寵物疼痛和發炎的藥物。 重要給藥指引： • 遵守給藥時間表： 如果您的獸醫師開立了每週的給藥計畫（例如，連續給藥 3 到 5 天，然後在一週的剩餘時間停藥），務必嚴格遵守。這種「脈衝式」給藥計畫有助於預防嚴重的副作用。 • 與食物一起餵食： 將此藥物與食物一起餵食可以幫助您的寵物更好地吸收，並可能減少腸胃不適。 • 注意事項： 如果您的寵物出現嘔吐、腹瀉、食慾不振、飲水量或排尿量增加，或者您發現深色柏油狀糞便（這可能是胃出血的跡象），請立即停藥並聯絡您的獸醫師。 • 請勿混合用藥： 在寵物服用托芬那酸期間，絕對不要給予人類的止痛藥（如阿斯匹靈或布洛芬）或其他獸醫用 NSAID，因為這可能會導致致命的胃潰瘍或腎衰竭。
托芬那酸對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。