Tepoxalin
別名: Zubrin
* **Administration**: Place the tablet directly into your dog's mouth and hold the mouth closed for approximately 4 seconds. The tablet is designed to disintegrate rapidly in saliva, preventing the dog from spitting it out. * **Food**: Give this medication with food to improve absorption and potentially reduce stomach upset. * **Hydration**: Ensure your dog always has access to fresh water. Dehydration increases the risk of kidney side effects. > **Important**: Stop the medication immediately and contact your veterinarian if you notice severe or persistent vomiting, diarrhea, black/tarry stools, loss of appetite, lethargy, or yellowing of the gums/eyes (jaundice).
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Pain and inflammation associated with osteoarthritis
給藥方式
可能的副作用
- Diarrhea
- Vomiting
- Anorexia/inappetence
- Enteritis
- Lethargy
- Incoordination (<1%)
- Incontinence (<1%)
- Increased appetite (<1%)
- Eating grass (<1%)
- Flatulence (<1%)
- Hair loss (<1%)
- Trembling (<1%)
注意事項與禁忌
- Prior hypersensitivity reactions to tepoxalin
- Active gastrointestinal ulcers
- Dogs weighing less than 3 kg (cannot be accurately dosed)
- Dogs less than 6 months old (safety not established)
- Use with caution in patients with impaired hepatic, cardiovascular, or renal function, or those at risk for developing nephrotoxic effects associated with NSAIDs (e.g., dehydrated patients or those on concomitant diuretic therapy). Safety has not been determined in pregnant, breeding, or lactating dogs; use with caution and informed consent. Discontinue if signs of inappetence, vomiting, fecal abnormalities, anemia, icterus, or lethargy are observed.
藥物相互作用
- Aspirin: May increase the risk of gastrointestinal toxicity (e.g., ulceration, bleeding, vomiting, diarrhea)
- Corticosteroids: May increase the occurrence of gastric ulceration; avoid concomitant use
- Digoxin: NSAIDs may increase serum levels of digoxin
- Fluconazole: May increase plasma levels of tepoxalin (extrapolated from human celecoxib data)
- Furosemide: NSAIDs may reduce saluretic and diuretic effects
- Methotrexate: Serious toxicity has occurred with concomitant NSAID use; use with extreme caution
- Nephrotoxic Drugs (e.g., aminoglycosides, amphotericin B): May enhance the risk of nephrotoxicity
- Other NSAIDs: May increase the risk of gastrointestinal toxicity (e.g., ulceration, bleeding, vomiting, diarrhea)
- Warfarin: Tepoxalin is highly protein bound (98-99%); may displace warfarin and increase bleeding risk. Monitor closely.
常見問題
Tepoxalin用於寵物有甚麼用途？
* **Administration**: Place the tablet directly into your dog's mouth and hold the mouth closed for approximately 4 seconds. The tablet is designed to disintegrate rapidly in saliva, preventing the dog from spitting it out. * **Food**: Give this medication with food to improve absorption and potentially reduce stomach upset. * **Hydration**: Ensure your dog always has access to fresh water. Dehydration increases the risk of kidney side effects. > **Important**: Stop the medication immediately and contact your veterinarian if you notice severe or persistent vomiting, diarrhea, black/tarry stools, loss of appetite, lethargy, or yellowing of the gums/eyes (jaundice).
Tepoxalin對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。