Sodium Stibogluconate
別名: Pentostam
* **Public Health:** Clients should understand the potential zoonotic and public health implications of leishmaniasis in dogs, which is highly dependent on the country and local vectors. * **Prognosis:** The prognosis for dogs with leishmaniasis remains **guarded**, even with aggressive treatment. Relapses are common. * **Risks & Costs:** Treatment carries a risk of severe side effects and can be financially demanding. Close monitoring by your veterinarian is essential.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Treatment of cutaneous leishmaniasis
- Treatment of visceral leishmaniasis
給藥方式
可能的副作用
- Increased AST levels
- Pain on injection
- Musculoskeletal pain
- Hemolytic anemia
- Leukopenia
- Vomiting
- Diarrhea
- Pancreatitis
- Myocardial injury and arrhythmias
- Renal toxicity
- Shock
- Sudden death
- Thrombophlebitis (with IV administration)
- Nephrotoxicity
- Hepatotoxicity
注意事項與禁忌
- Pre-existing cardiac arrhythmias
- Significantly impaired renal function
- Previous serious adverse reaction to a dose of stibogluconate
- Severe renal impairment
- Severe hepatic impairment
- **Contraindicated** in patients with pre-existing cardiac arrhythmias or significantly impaired renal function. * **Duration Warning:** The incidence of adverse effects reportedly increases significantly if the drug is administered for longer than 2 months. * **Pregnancy:** Has not been shown to cause fetal harm, but should be withheld during pregnancy unless the benefits clearly outweigh the risks. * **Nursing:** Controversial; the manufacturer states it should not be used in nursing mothers, though some human pediatric guidelines consider it compatible.
藥物相互作用
- Amphotericin B: Increased risk of nephrotoxicity
- Allopurinol: Synergistic antileishmanial effect (often used together clinically)
常見問題
Sodium Stibogluconate用於寵物有甚麼用途？
* **Public Health:** Clients should understand the potential zoonotic and public health implications of leishmaniasis in dogs, which is highly dependent on the country and local vectors. * **Prognosis:** The prognosis for dogs with leishmaniasis remains **guarded**, even with aggressive treatment. Relapses are common. * **Risks & Costs:** Treatment carries a risk of severe side effects and can be financially demanding. Close monitoring by your veterinarian is essential.
Sodium Stibogluconate對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。