Sodium Polystyrene Sulfonate
別名: Kayexalate, Kionex, SPS, Elutit-Natrium, KExit, Kexelate, Resinsodio, Resonium, Resonium A
Sodium Polystyrene Sulfonate is used to help lower dangerously high potassium levels in your pet's blood. * **Administration:** This medication can be given by mouth or as an enema. If given by mouth, it is often mixed with a sweet liquid (sorbitol) to help it move through the digestive tract and prevent constipation. Shake liquid suspensions very well before each use. * **Side Effects:** Watch for signs of constipation, loss of appetite, vomiting, or nausea. Contact your veterinarian if your pet stops having bowel movements. * **Interactions:** Do not give your pet over-the-counter antacids or laxatives (especially those containing calcium or magnesium, like Milk of Magnesia) while they are taking this medication, as it can cause dangerous changes in blood chemistry. * **Follow-up:** Your pet will need frequent blood tests to ensure their potassium and sodium levels remain in a safe range.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Life-threatening hyperkalemia in neonatal foals
- Hyperkalemia
- Mild hyperkalemia (<6 mEq/L)
給藥方式
可能的副作用
- Constipation (fecal impaction reported rarely)
- Anorexia
- Vomiting
- Nausea
- Hypokalemia (from overuse)
- Hypocalcemia
- Hypomagnesemia
- Sodium retention / Hypernatremia
注意事項與禁忌
- Patients on severely restricted sodium diets
- Severe congestive heart failure (CHF)
- Severe hypertension
- Oliguric or anuric acute kidney injury (where sodium load cannot be excreted)
- Conditions predisposing to severe constipation or bowel obstruction
- Because large quantities of **sodium** may be released and absorbed during the exchange process, use with extreme caution in patients requiring sodium restriction (e.g., severe CHF, hypertension). Overdosage or prolonged use can lead to severe electrolyte derangements, specifically **hypokalemia, hypocalcemia, and hypomagnesemia**. When given orally, it is generally mixed with a cathartic (like 70% sorbitol) to hasten transit time and prevent severe constipation or fecal impaction. However, **do not use a cathartic if administering as a retention enema**, as the resin must remain in the colon for at least 30 minutes to be effective.
藥物相互作用
- Antacids (Calcium or Magnesium containing): SPS may bind with magnesium or calcium, preventing bicarbonate ion neutralization and potentially leading to systemic metabolic alkalosis. Concurrent use is not recommended.
- Laxatives (Calcium or Magnesium containing): Similar to antacids, can lead to metabolic alkalosis and reduced potassium-binding efficacy.
常見問題
Sodium Polystyrene Sulfonate用於寵物有甚麼用途？
Sodium Polystyrene Sulfonate is used to help lower dangerously high potassium levels in your pet's blood. * **Administration:** This medication can be given by mouth or as an enema. If given by mouth, it is often mixed with a sweet liquid (sorbitol) to help it move through the digestive tract and prevent constipation. Shake liquid suspensions very well before each use. * **Side Effects:** Watch for signs of constipation, loss of appetite, vomiting, or nausea. Contact your veterinarian if your pet stops having bowel movements. * **Interactions:** Do not give your pet over-the-counter antacids or laxatives (especially those containing calcium or magnesium, like Milk of Magnesia) while they are taking this medication, as it can cause dangerous changes in blood chemistry. * **Follow-up:** Your pet will need frequent blood tests to ensure their potassium and sodium levels remain in a safe range.
Sodium Polystyrene Sulfonate對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。