Romifidine
別名: Sedivet, Romidys, Sedivan
* **Professional Use Only**: This medication is strictly administered by veterinary professionals in a clinical setting. * **Caution Around Sedated Horses**: If you are assisting with or handling a horse that has received romifidine, **exercise extreme caution**. Even if the horse appears deeply asleep or heavily sedated, it can still react suddenly and defensively (e.g., kicking or striking) if startled by loud noises or sudden touch. * **Fasting for Pets**: If your dog or cat is scheduled to receive this medication, your veterinarian will likely recommend withholding food for at least 12 hours beforehand, as the drug frequently causes nausea and vomiting shortly after administration.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- For sedation
- As a preanesthetic
- As an analgesic adjunct
- For epidural anesthesia for paralumbar analgesia or laparotomy
- For sedation and analgesia
- As a preanesthetic
- For sedation
- As a preanesthetic
- As an analgesic adjunct
給藥方式
可能的副作用
- Bradycardia (can be profound)
- First- and second-degree atrioventricular (AV) heart block
- Sinus arrhythmias
- Initial hypertension followed by hypotension
- Ataxia and muscle tremors
- Sweating and piloerection (horses)
- Vomiting (especially common in cats)
- Transient hyperglycemia
- Decreased gastrointestinal motility (flatulence, mild colic in horses)
- Increased urination
- Altered thermoregulation (hypothermia or hyperthermia)
- Swelling of face, lips, and upper airways; stridor (horses)
- Paradoxical excitation (rare)
注意事項與禁忌
- Known hypersensitivity to romifidine
- Concurrent use with intravenous potentiated sulfonamides
- Preexisting cardiac conditions, arrhythmias, or severe cardiovascular compromise
- Severe respiratory, hepatic, or renal disease
- Pregnancy (especially last month in horses, and throughout pregnancy in dogs/cats)
- Shock or severe systemic debilitation
- **Important Warnings:** * **Sudden Arousal**: Animals may appear deeply sedated but can still respond aggressively (e.g., kicking) to external stimuli. Use appropriate physical restraint. * **Cardiovascular Depression**: Causes significant bradycardia and AV block. Use with extreme caution in patients with preexisting heart disease. * **Vomiting Risk**: Dogs and particularly cats may vomit after administration. Fasting for at least 12 hours prior to use is recommended in small animals. * **Thermoregulation**: Can cause hypothermia during prolonged sedation; provide thermal support. * **Human Safety**: Can be absorbed through the skin and oral mucosa. Handlers should avoid self-exposure and wash immediately if accidental contact occurs.
藥物相互作用
- Intravenous Potentiated Sulfonamides (e.g., trimethoprim/sulfa): May cause fatal dysrhythmias; concurrent use is strictly contraindicated.
- Other Alpha-2 Agonists (e.g., xylazine, dexmedetomidine) & Epinephrine: Additive cardiovascular and CNS effects; epinephrine may potentiate adverse effects and arrhythmias.
- Phenothiazines (e.g., acepromazine): Can result in severe, compounding hypotension.
- Anesthetics, Opiates, Sedatives/Hypnotics: Synergistic CNS depression; significantly reduces the required dose of induction and maintenance anesthetics. Increased risk of arrhythmias with thiopental, ketamine, or halothane.
常見問題
Romifidine用於寵物有甚麼用途？
* **Professional Use Only**: This medication is strictly administered by veterinary professionals in a clinical setting. * **Caution Around Sedated Horses**: If you are assisting with or handling a horse that has received romifidine, **exercise extreme caution**. Even if the horse appears deeply asleep or heavily sedated, it can still react suddenly and defensively (e.g., kicking or striking) if startled by loud noises or sudden touch. * **Fasting for Pets**: If your dog or cat is scheduled to receive this medication, your veterinarian will likely recommend withholding food for at least 12 hours beforehand, as the drug frequently causes nausea and vomiting shortly after administration.
Romifidine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。