Rocuronium Bromide
別名: Zemuron, Esmeron
Rocuronium is a specialized medication used strictly in a hospital setting during general anesthesia. * **Purpose**: It is a muscle relaxant that temporarily paralyzes the skeletal muscles. This is crucial for certain delicate surgeries (like eye, brain, or chest surgery) where even a small reflex twitch could be dangerous. * **Safety**: Your pet will be completely asleep and unaware (fully anesthetized) before this drug is given. Because it relaxes the breathing muscles, the veterinary team will place a breathing tube and use a mechanical ventilator to breathe for your pet while the drug is in effect. * **Recovery**: The effects of the drug wear off naturally, or the veterinarian can give a specific reversal agent to wake the muscles up quickly once the surgery is safely completed.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As a neuromuscular blocker
- Neuromuscular blockade / Endotracheal intubation
- As a neuromuscular blocker
- As a neuromuscular blocker
- Neuromuscular blockade during anaesthesia
- Centralize the globe for ophthalmic surgery
給藥方式
可能的副作用
- Changes in heart rate (mild, transient tachycardia)
- Changes in blood pressure (hypotension or hypertension)
- Severe anaphylaxis (reported in humans)
- Histaminoid reactions (rare)
- Severe burning pain at the injection site (if administered before deep anesthesia is achieved)
- Increased heart rate
- Mild hypertension (at high doses)
注意事項與禁忌
- Hypersensitivity to rocuronium or other neuromuscular blocking agents
- Patients who are not adequately anesthetized or sedated
- Settings lacking immediate access to intubation, mechanical ventilation, and oxygen therapy
- Conscious or inadequately anaesthetized animals
- Lack of positive pressure ventilation facilities
- Rocuronium must **only** be used by trained personnel in settings where the patient can be fully monitored and where endotracheal intubation, mechanical ventilation, oxygen therapy, and reversal agents are immediately available. It should only be administered to patients that are **adequately anesthetized or sedated**. Because the drug can cause severe burning pain upon injection, it is recommended to administer it only after a deep stage of anesthesia has been achieved. Use with caution in patients with hepatic or renal impairment, as elimination may be delayed (some sources prefer atracurium in these patients).
藥物相互作用
- Other Non-depolarizing Muscle Relaxants: May have a synergistic effect if used concurrently with rocuronium.
- Succinylcholine: May speed the onset of action and enhance the neuromuscular blocking actions of rocuronium; do not give rocuronium until succinylcholine effects have subsided.
- Aminoglycosides (e.g., gentamicin, amikacin): May enhance or prolong the neuromuscular blocking activity of rocuronium.
- Inhalant Anesthetics (halothane, isoflurane, sevoflurane): May enhance or prolong the neuromuscular blocking activity of rocuronium.
- Clindamycin, Lincomycin: May enhance or prolong the neuromuscular blocking activity of rocuronium.
- Dantrolene: May enhance or prolong the neuromuscular blocking activity of rocuronium.
- Magnesium Salts: May enhance or prolong the neuromuscular blocking activity of rocuronium.
- Piperacillin, Mezlocillin: May enhance or prolong the neuromuscular blocking activity of rocuronium.
- Quinidine: May enhance or prolong the neuromuscular blocking activity of rocuronium.
- Tetracyclines: May enhance or prolong the neuromuscular blocking activity of rocuronium.
常見問題
Rocuronium Bromide用於寵物有甚麼用途？
Rocuronium is a specialized medication used strictly in a hospital setting during general anesthesia. * **Purpose**: It is a muscle relaxant that temporarily paralyzes the skeletal muscles. This is crucial for certain delicate surgeries (like eye, brain, or chest surgery) where even a small reflex twitch could be dangerous. * **Safety**: Your pet will be completely asleep and unaware (fully anesthetized) before this drug is given. Because it relaxes the breathing muscles, the veterinary team will place a breathing tube and use a mechanical ventilator to breathe for your pet while the drug is in effect. * **Recovery**: The effects of the drug wear off naturally, or the veterinarian can give a specific reversal agent to wake the muscles up quickly once the surgery is safely completed.
Rocuronium Bromide對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。