Propranolol
別名: Inderal, Inderal LA, InnoPran XL, Syprol
* **Consistency is Key:** To be effective, your pet must receive all doses exactly as prescribed by your veterinarian. Do not abruptly stop this medication without consulting your vet, as it can cause a dangerous rebound effect on the heart. * **What to Watch For:** Contact your veterinarian immediately if your pet becomes unusually lethargic, tires easily during exercise, begins wheezing, develops shortness of breath or a cough, or shows a sudden change in behavior or attitude. * **Missed Doses:** If you miss a dose, give it as soon as you remember, but never give two doses at once.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Susceptible cardiac arrhythmias
- Susceptible cardiac arrhythmias
- Susceptible cardiac arrhythmias
- Adjunctive therapy in heart failure
- Adjunctive therapy of hypertension
- Adjunctive therapy in feline hyperthyroidism
- Hypertrophic cardiomyopathy
- Hypertrophic cardiomyopathy
- V-Tach
- V-Tach
- V-Tach
- Cardiac arrhythmias
- Cardiac arrhythmias
- Susceptible cardiac arrhythmias
給藥方式
可能的副作用
- Bradycardia
- Lethargy and depression
- Impaired AV conduction
- Congestive heart failure (CHF) or worsening of heart failure
- Hypotension
- Syncope
- Diarrhea
- Hypoglycemia
- Bronchoconstriction
- AV block
- Myocardial depression
- Heart failure
- Hypoglycaemia
- Bronchospasm
- Diarrhoea
注意事項與禁忌
- Overt heart failure
- Hypersensitivity to beta-blockers
- Greater than 1st degree heart block
- Sinus bradycardia
- Congestive heart failure (unless secondary to a tachyarrhythmia responsive to beta-blockers)
- Bronchospastic lung disease (e.g., feline asthma)
- Bradyarrhythmias
- Acute or decompensated congestive heart failure
- Concurrent administration with alpha-adrenergic agonists (e.g., adrenaline)
- **Use with Caution:** * Patients with significant renal or hepatic insufficiency. * Patients with sinus node dysfunction. * Labile diabetic patients (can cause or mask clinical signs of hypoglycemia). * Digitalized or digitalis-intoxicated patients (severe bradycardia may result). * May mask clinical signs of thyrotoxicosis. * **Withdrawal:** If discontinuing the drug after chronic use, gradual withdrawal is recommended to prevent exacerbation of clinical signs.
藥物相互作用
- Antacids: May reduce oral propranolol absorption; separate doses by at least one hour
- Anesthetics, General: Additive myocardial depression may occur
- Anticholinergics: May negate cardiac effects of beta-blockers
- Calcium Channel Blockers: Concurrent use should be done with caution due to additive negative inotropic effects, particularly in patients with cardiomyopathy or CHF
- Cimetidine: May decrease the metabolism of propranolol and increase blood levels
- Diuretics: May increase risk for hypotension
- Epinephrine: Unopposed alpha effects of epinephrine may lead to rapid increases in blood pressure and decrease in heart rate
- Fluoxetine: May decrease propranolol metabolism; complete heart block reported in one human
- Insulin and Antidiabetic Drugs: Propranolol may prolong the hypoglycemic effects of insulin therapy
- Lidocaine: Clearance may be impaired by propranolol
- Methimazole, Propylthiouracil: Propranolol doses may need to be decreased when initiating therapy
常見問題
Propranolol用於寵物有甚麼用途？
* **Consistency is Key:** To be effective, your pet must receive all doses exactly as prescribed by your veterinarian. Do not abruptly stop this medication without consulting your vet, as it can cause a dangerous rebound effect on the heart. * **What to Watch For:** Contact your veterinarian immediately if your pet becomes unusually lethargic, tires easily during exercise, begins wheezing, develops shortness of breath or a cough, or shows a sudden change in behavior or attitude. * **Missed Doses:** If you miss a dose, give it as soon as you remember, but never give two doses at once.
Propranolol對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。