Prochlorperazine
別名: Compazine, Compro, Prochlor, Prorazin, Stemetil, Tementil
> **Important Safety Note:** Observe your pet closely for at least one hour following dosing. Keep them in a safe, quiet environment as this medication can cause drowsiness and unsteadiness. * **Dry Mouth:** Your pet may experience a dry mouth (often seen as lip smacking). This can be relieved by applying small amounts of water to your pet's tongue for 10-15 minutes. * **Urine Color Change:** This medication may harmlessly discolor the urine to a pink or red-brown color; this is normal and not a cause for concern. * **When to Call the Vet:** Protracted vomiting and diarrhea can be serious. Contact your veterinarian if clinical signs are not alleviated. **Seek immediate veterinary care** if your animal exhibits abnormal behavior, becomes rigid, or displays other abnormal body movements or tremors.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As an antiemetic
- As an antiemetic
- As an antiemetic
- All uses (motion sickness, emesis)
- All uses (motion sickness, emesis)
- As an antiemetic
- As an antiemetic
- As an antiemetic
- All uses (motion sickness, emesis)
- All uses (motion sickness, emesis)
給藥方式
可能的副作用
- Sedation
- Hypotension
- Muscle fasciculations and tremors (extrapyramidal signs)
- Prolactin release
- Depression
- Extrapyramidal reactions (rigidity, tremors, weakness, restlessness)
注意事項與禁忌
- Hypovolemia or dehydration
- Shock
- Tetanus
- Strychnine intoxication
- Hepatic dysfunction (use with caution)
- Cardiac disease (use with caution)
- Animals may require lower dosages of general anesthetics following phenothiazine administration. Use cautiously and at smaller doses in animals with hepatic dysfunction, cardiac disease, or general debilitation. Because of hypotensive effects, it is relatively contraindicated in patients with hypovolemia, dehydration, or shock. May exacerbate depression in patients with pre-existing CNS depression. Do not use for tetanus or strychnine intoxication due to extrapyramidal effects. Use with caution in very young or debilitated animals.
藥物相互作用
- Antacids: May cause reduced GI absorption of oral phenothiazines
- Antidiarrheal mixtures (e.g., Kaolin/pectin, bismuth subsalicylate): May cause reduced GI absorption of oral phenothiazines
- CNS Depressant Agents (barbiturates, narcotics, anesthetics): May cause additive CNS depression if used with phenothiazines
- Dopamine: Phenothiazines may decrease pressor effects
- Epinephrine: Phenothiazines block alpha-adrenergic receptors; concomitant epinephrine can lead to unopposed beta-activity causing vasodilation and increased cardiac rate (epinephrine reversal)
- Metoclopramide: Phenothiazines may potentiate the extrapyramidal effects of metoclopramide
- Opiates: May enhance the hypotensive effects of the phenothiazines; dosages of prochlorperazine may need to be reduced
- Organophosphate Agents: Phenothiazines should not be given within one month of worming with these agents as their effects may be potentiated
- Paraquat: Toxicity of the herbicide paraquat may be increased by prochlorperazine
- Phenytoin: Metabolism may be decreased if given concurrently with phenothiazines
常見問題
Prochlorperazine用於寵物有甚麼用途？
> **Important Safety Note:** Observe your pet closely for at least one hour following dosing. Keep them in a safe, quiet environment as this medication can cause drowsiness and unsteadiness. * **Dry Mouth:** Your pet may experience a dry mouth (often seen as lip smacking). This can be relieved by applying small amounts of water to your pet's tongue for 10-15 minutes. * **Urine Color Change:** This medication may harmlessly discolor the urine to a pink or red-brown color; this is normal and not a cause for concern. * **When to Call the Vet:** Protracted vomiting and diarrhea can be serious. Contact your veterinarian if clinical signs are not alleviated. **Seek immediate veterinary care** if your animal exhibits abnormal behavior, becomes rigid, or displays other abnormal body movements or tremors.
Prochlorperazine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。