Primaquine
別名: Generic (Sanofi Winthrop)
- **Strict Dosing**: This medication has a very low safety margin when used in cats. Exact adherence to the prescribed dosage is extremely important. **Never** double-up the next dose if a dose was previously missed. - **Administration**: Give the dose with food to reduce the chance of gastrointestinal problems, particularly vomiting. - **Monitoring**: Watch your pet closely for signs of lethargy, pale or discolored gums, or breathing difficulties, and report any abnormalities to your veterinarian immediately.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Babesia felis
- Babesia felis
- Babesia felis
給藥方式
可能的副作用
- Vomiting (most common in cats)
- Nausea
- Myelosuppression
- Methemoglobinemia
- Hemolysis
注意事項與禁忌
- Known hypersensitivity to primaquine
- Concurrent use of bone marrow suppressant medications
- Patients susceptible to granulocytopenia (e.g., lupus, rheumatoid arthritis)
- Glucose-6-Phosphate Dehydrogenase (G-6-PD) deficiency
- Pregnancy
- Lactation
- > **WARNING**: Primaquine has an extremely narrow therapeutic index in cats. - **Dosing Confusion**: Commercially available human tablets are usually too concentrated for domestic cats. A specialized compounding pharmacy is highly recommended. Prescribers must be explicitly clear whether the dose is based on **primaquine base** or **primaquine phosphate** (26.3 mg primaquine phosphate = 15 mg primaquine base). - **G-6-PD Deficiency**: Contraindicated in humans (and theoretically animals) with Glucose-6-Phosphate Dehydrogenase deficiency due to severe risk of hemolytic anemia. - Avoid use during pregnancy and lactation due to the risk of hemolytic anemia in fetuses/nursing neonates.
藥物相互作用
- Quinacrine: May potentiate the toxicity of one another; use of primaquine within 3 months of quinacrine is not recommended.
- Bone Marrow Depressants (e.g., amphotericin B, azathioprine, chloramphenicol, antineoplastics): Concurrent use may cause an increased risk for toxicity and severe myelosuppression.
- Hemolytic Drugs (e.g., acetohydroxamic acid, sulfonylureas, quinidine, sulfonamides): Concurrent use may cause an increased risk for toxicity and hemolysis.
常見問題
Primaquine用於寵物有甚麼用途？
- **Strict Dosing**: This medication has a very low safety margin when used in cats. Exact adherence to the prescribed dosage is extremely important. **Never** double-up the next dose if a dose was previously missed. - **Administration**: Give the dose with food to reduce the chance of gastrointestinal problems, particularly vomiting. - **Monitoring**: Watch your pet closely for signs of lethargy, pale or discolored gums, or breathing difficulties, and report any abnormalities to your veterinarian immediately.
Primaquine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。