Pentobarbital Sodium
別名: Nembutal
**Important Information for Pet Owners:** * **Post-Anesthesia Care:** Your pet may experience a rough recovery (vocalization, paddling, or excitement) as the drug wears off. Keep them in a quiet, dimly lit, and safe environment to prevent injury. * **Temperature Control:** Pentobarbital can lower body temperature. Keep your pet warm and comfortable, but avoid direct heat sources like heating pads which can cause burns. * **Nursing Pets:** This medication passes into breast milk and can cause drowsiness in nursing newborns. * **Toxicity Warning:** Never allow pets to scavenge or consume the remains of animals that have been euthanized. Pentobarbital persists in tissues and can cause fatal poisoning if ingested.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
給藥方式
可能的副作用
- Respiratory depression (can be severe)
- Hypothermia
- Paradoxical excitement during recovery (especially in dogs)
- Cardiovascular depression (decreased contractility, hypotension)
- Severe tissue irritation and necrosis (if given perivascularly or SC)
注意事項與禁忌
- Known hypersensitivity to barbiturates
- Severe liver disease
- Nephritis
- Severe respiratory depression
- Lidocaine-induced seizures
- Pregnancy (Category D - embryotoxic/teratogenic)
- Administer IV SLOWLY (unless used for euthanasia). Very irritating if given SC or perivascularly; do NOT give intra-arterially (IA). Use cautiously in patients who are hypovolemic, anemic, or have borderline hypoadrenal, cardiac, or respiratory disease. Cats (especially females) are particularly sensitive to respiratory depressant effects. Use with caution in neonates due to higher CNS penetration.
藥物相互作用
- Acetaminophen: Increased risk for hepatotoxicity, particularly with large or chronic barbiturate doses.
- Lidocaine: Fatalities reported when treating lidocaine-induced seizures with pentobarbital; use diazepam instead.
- Phenytoin: Barbiturates may affect phenytoin metabolism and vice versa; blood level monitoring indicated.
- Rifampin: May induce enzymes that increase the metabolism of barbiturates.
- Antihistamines: May increase the CNS depressant effect of pentobarbital.
- Chloramphenicol: May increase the CNS depressant effect of pentobarbital.
- Opiates: May increase the CNS depressant effect of pentobarbital.
- Phenothiazines: May increase the CNS depressant effect of pentobarbital.
常見問題
Pentobarbital Sodium用於寵物有甚麼用途？
**Important Information for Pet Owners:** * **Post-Anesthesia Care:** Your pet may experience a rough recovery (vocalization, paddling, or excitement) as the drug wears off. Keep them in a quiet, dimly lit, and safe environment to prevent injury. * **Temperature Control:** Pentobarbital can lower body temperature. Keep your pet warm and comfortable, but avoid direct heat sources like heating pads which can cause burns. * **Nursing Pets:** This medication passes into breast milk and can cause drowsiness in nursing newborns. * **Toxicity Warning:** Never allow pets to scavenge or consume the remains of animals that have been euthanized. Pentobarbital persists in tissues and can cause fatal poisoning if ingested.
Pentobarbital Sodium對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。