Pantoprazole
別名: Protonix, Pantoloc, Controloc, Zurcal, Pantozol, Pantop, Protium, Somac-MA
> **Important:** Tablets must be given whole; do not split, crush, or allow your pet to chew them. The special coating protects the drug from being destroyed by stomach acid before it can be absorbed. * Administer exactly as directed by your veterinarian. * **Monitor for severe signs:** If your pet develops bloody diarrhea, tarry-black stools (melena), or vomits blood (or material that looks like coffee grounds), contact your veterinarian immediately. * Contact your veterinarian if vomiting or diarrhea persists or becomes severe.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Gastric acid suppression
- All uses (ulcers, oesophagitis, hypersecretory conditions)
- Gastric acid suppression in neonatal foals
- Intravenous treatment of stress-related mucosal disease
- Gastric acid suppression
- All uses (ulcers, oesophagitis, hypersecretory conditions)
給藥方式
可能的副作用
- Diarrhea
- Headache (reported in humans)
- Hyperglycemia (rare, ~1% in humans)
- Injection site reactions (thrombophlebitis, abscess) with IV use
- Potential increased risk of community-acquired pneumonia (noted in human literature)
- Diarrhoea
- Headache
- Hyperglycaemia (rare)
- Increased risk of pneumonia
- Thrombophlebitis (associated with IV injection)
注意事項與禁忌
- Known hypersensitivity to pantoprazole or other substituted benzimidazole PPIs
- Intramuscular (IM) or Subcutaneous (SQ) administration (parenteral form must be given IV)
- Intramuscular (IM) administration
- Subcutaneous (SC) administration
- Parenteral pantoprazole MUST be administered IV; do not give IM or SQ. Reconstituted injection (4 mg/mL) must be administered intravenously over not less than 2 minutes. Use with caution in pregnant animals (FDA Category B in humans) though animal studies have not demonstrated teratogenic effects. May cause false-positive results for urine screening tests for THC.
藥物相互作用
- Ketoconazole, itraconazole, iron, ampicillin esters: Decreased drug absorption due to increased gastric pH (these drugs require an acidic environment for optimal absorption)
- Sucralfate: May decrease the bioavailability of orally administered pantoprazole
- Warfarin: Pantoprazole may increase the anticoagulant effect
- Itraconazole: Decreased absorption of itraconazole due to increased gastric pH
- Ketoconazole: Decreased absorption of ketoconazole due to increased gastric pH
常見問題
Pantoprazole用於寵物有甚麼用途？
> **Important:** Tablets must be given whole; do not split, crush, or allow your pet to chew them. The special coating protects the drug from being destroyed by stomach acid before it can be absorbed. * Administer exactly as directed by your veterinarian. * **Monitor for severe signs:** If your pet develops bloody diarrhea, tarry-black stools (melena), or vomits blood (or material that looks like coffee grounds), contact your veterinarian immediately. * Contact your veterinarian if vomiting or diarrhea persists or becomes severe.
Pantoprazole對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。