Nitroprusside Sodium
別名: Nitropress
> **Intensive Care Medication** * This medication is strictly for use by veterinary professionals in an Intensive Care Unit (ICU) setting. * It requires precise intravenous delivery via a specialized pump and continuous, minute-by-minute monitoring of your pet's blood pressure. * It is a life-saving drug used to rapidly stabilize pets in severe heart failure or experiencing dangerously high blood pressure crises. * Because it is so potent, the veterinary team will monitor your pet closely for any signs of low blood pressure or side effects from the medication's breakdown products.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Hypertensive crisis (systolic arterial BP >200 mm Hg)
- Adjunctive treatment of heart failure (cardiogenic shock; fulminant pulmonary edema)
- Adjunctive treatment of heart failure
- Catastrophic pulmonary edema
- Hypertensive crisis (systolic arterial BP >200 mm Hg)
- Adjunctive treatment of heart failure (cardiogenic shock; fulminant pulmonary edema)
- Adjunctive treatment of heart failure
- Catastrophic pulmonary edema
給藥方式
可能的副作用
- Profound hypotension
- Nausea
- Retching
- Restlessness
- Apprehension
- Muscle twitching
- Dizziness
- Infusion site irritation (avoid extravasation)
- Thiocyanate and cyanide toxicity (with prolonged use)
注意事項與禁忌
- Compensatory hypertension (e.g., AV shunts, coarctation of the aorta, Cushing's reflex)
- Inadequate cerebral circulation
- Emergency surgery in patients near death
- > **CRITICAL WARNING**: Must only be used in an ICU setting with continuous blood pressure monitoring. * **Organ Impairment**: Use with extreme caution in patients with hepatic insufficiency, severe renal impairment, hyponatremia, or hypothyroidism due to increased risk of thiocyanate/cyanide toxicity. * **Surgical Use**: When used for controlled hypotension during surgery, patients have less tolerance to hypovolemia, anemia, or blood loss. * **Geriatrics**: Older patients may be more sensitive to hypotensive effects. * **Pregnancy**: FDA Category C. Animal studies show adverse fetal effects. Use cautiously as a last resort when benefits clearly outweigh risks. Unknown if excreted in milk.
藥物相互作用
- General Anesthetics (e.g., halothane, enflurane): May enhance the hypotensive effects of nitroprusside.
- Dobutamine: Synergistic effects (increased cardiac output and reduced wedge pressure) may result; often used together beneficially in severe heart failure.
- Other Hypotensive Agents (e.g., beta-blockers, ACE inhibitors): Patients may be more sensitive to the hypotensive effects of nitroprusside.
常見問題
Nitroprusside Sodium用於寵物有甚麼用途？
> **Intensive Care Medication** * This medication is strictly for use by veterinary professionals in an Intensive Care Unit (ICU) setting. * It requires precise intravenous delivery via a specialized pump and continuous, minute-by-minute monitoring of your pet's blood pressure. * It is a life-saving drug used to rapidly stabilize pets in severe heart failure or experiencing dangerously high blood pressure crises. * Because it is so potent, the veterinary team will monitor your pet closely for any signs of low blood pressure or side effects from the medication's breakdown products.
Nitroprusside Sodium對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。