Methionine
別名: Ammonil, Acimethin, Acimol, M-Caps, Methigel, Methio-Form, Methiotrans, Methnine, Neutrodor, Pedameth, Uracid, Uromethin, Uroeze
* **Administration:** Give this medication with meals or mixed directly into your pet's food to reduce stomach upset and enhance effectiveness. * > **Important Warning:** Do not give to kittens, and ensure kittens cannot access adult cat food that has been treated with this medication. * **Dietary Caution:** Do not combine this medication with prescription urinary diets (like s/d or c/d) unless specifically instructed by your veterinarian, as this can cause dangerous changes in blood acid levels. * **When to Call the Vet:** Contact your veterinarian immediately if your cat shows signs of weakness, loss of appetite, uncoordinated walking, or pale/bluish gums.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Urine acidification
- Urine acidification
- General / Ketosis
- Laminitis (purported)
- Senecio-induced liver damage
- Urine acidification (struvite dissolution)
- Struvite dissolution therapy (if diet and antimicrobials do not result in acid urine)
給藥方式
可能的副作用
- Gastrointestinal distress (nausea, vomiting)
- Heinz-body hemolytic anemia (especially in cats)
- Methemoglobinemia
- Ataxia
- Cyanosis
- Metabolic acidosis
- Gastrointestinal upset (nausea, vomiting, diarrhea)
- Heinz body anemia (especially in cats at high doses)
- Worsening of hepatic encephalopathy in patients with liver disease
注意事項與禁忌
- Renal failure
- Pancreatic disease
- Hepatic insufficiency
- Preexisting acidosis
- Oxalate or urate calculi
- Kittens
- Pre-existing metabolic acidosis
- Severe liver disease or hepatic encephalopathy
- Urate, cystine, or calcium oxalate urolithiasis
- Young growing animals
- Pregnant or nursing animals
- > **Hepatic Warning:** If used in patients with frank hepatic insufficiency, methionine can cause increased production of mercaptan-like compounds and intensify the signs of **hepatic encephalopathy** (dementia or coma). * **Urolithiasis Risk:** Do not give to animals with oxalate or urate calculi, as these stones thrive in acidic environments. * **Dietary Overlap:** Unmonitored use concurrently with an acidifying diet (e.g., s/d, c/d) may easily lead to severe metabolic acidosis and signs of overdose. * **Age Restrictions:** Strictly not recommended for use in kittens due to high susceptibility to toxicity.
藥物相互作用
- Aminoglycosides (gentamicin, amikacin): Urine acidification may diminish the effectiveness of aminoglycosides in treating bacterial urinary tract infections, as they are more effective in an alkaline medium.
- Erythromycin: Urine acidification may diminish the effectiveness of erythromycin in treating bacterial urinary tract infections.
- Quinidine: Urine acidification may increase the renal excretion of quinidine, potentially lowering its systemic levels.
- Other urinary acidifiers (e.g., ammonium chloride): Additive acidification leading to severe metabolic acidosis
- Urinary acidifying diets: Excessive lowering of urine pH and increased risk of metabolic acidosis
常見問題
Methionine用於寵物有甚麼用途？
* **Administration:** Give this medication with meals or mixed directly into your pet's food to reduce stomach upset and enhance effectiveness. * > **Important Warning:** Do not give to kittens, and ensure kittens cannot access adult cat food that has been treated with this medication. * **Dietary Caution:** Do not combine this medication with prescription urinary diets (like s/d or c/d) unless specifically instructed by your veterinarian, as this can cause dangerous changes in blood acid levels. * **When to Call the Vet:** Contact your veterinarian immediately if your cat shows signs of weakness, loss of appetite, uncoordinated walking, or pale/bluish gums.
Methionine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。