Liothyronine Sodium
別名: Cytomel, Triostat, Tertroxin
> **Important:** Give this medication exactly as prescribed by your veterinarian. Do not change the dose or stop the medication without consulting them. * **What it is:** A synthetic thyroid hormone used to treat underactive thyroid glands (hypothyroidism) when standard treatments don't work. * **Dosing Schedule:** Because it doesn't last long in the body, it usually needs to be given 2 to 3 times a day. Consistency is key. * **What to watch for:** Contact your veterinarian if you notice signs that the dose might be too high. These include **excessive panting, pacing, nervousness, increased thirst and urination, a ravenous appetite, or a racing heart rate**. In cats, watch for unusual lethargy or loss of appetite. * **Follow-up:** Your pet will need periodic blood tests to ensure the dose is correct. The timing of the blood draw relative to when you give the pill is very important, so follow your clinic's instructions carefully.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Hypothyroidism
- T3 suppression test (diagnostic for hyperthyroidism)
- Hypothyroidism (unresponsive to T4)
- Hypothyroidism (refractory to T4)
給藥方式
可能的副作用
- Tachycardia
- Polyphagia
- Polyuria/Polydipsia (PU/PD)
- Excitability
- Nervousness
- Excessive panting
- Apathy or listlessness (seen in about 10% of cats)
- PU/PD (Polyuria/Polydipsia)
- Nervousness/Anxiety
- Panting
- Weight loss
注意事項與禁忌
- Acute myocardial infarction
- Thyrotoxicosis
- Untreated adrenal insufficiency
- Untreated adrenal insufficiency (Addison's disease)
- Use with extreme caution and at a lower initial dosage in patients with concurrent hypoadrenocorticism (must be treated first), cardiac disease, diabetes mellitus, or in elderly patients. Combination products containing both T3 and T4 should generally be avoided due to the risk of iatrogenic thyrotoxicosis.
藥物相互作用
- Tricyclic/Tetracyclic Antidepressants: Increased risk for CNS stimulation and cardiac arrhythmias.
- Antidiabetic Agents (insulin, oral agents): Thyroid hormones may increase the requirements for insulin or oral antidiabetic agents.
- Cholestyramine: May reduce liothyronine absorption; separate doses by at least 4 hours.
- Sympathomimetic Agents (epinephrine, norepinephrine): Thyroid hormones can potentiate the cardiovascular effects of sympathomimetics.
- Warfarin: Thyroid hormones increase the catabolism of vitamin K-dependent clotting factors, potentially increasing anticoagulation effects.
- Digoxin: Potential for reduced digoxin levels and decreased therapeutic effect.
- Ketamine: Concurrent use may cause tachycardia and hypertension.
- Sympathomimetics: Increased risk of cardiac arrhythmias and coronary insufficiency
- Insulin: May alter glucose control, requiring dosage adjustments
常見問題
Liothyronine Sodium用於寵物有甚麼用途?
> **Important:** Give this medication exactly as prescribed by your veterinarian. Do not change the dose or stop the medication without consulting them. * **What it is:** A synthetic thyroid hormone used to treat underactive thyroid glands (hypothyroidism) when standard treatments don't work. * **Dosing Schedule:** Because it doesn't last long in the body, it usually needs to be given 2 to 3 times a day. Consistency is key. * **What to watch for:** Contact your veterinarian if you notice signs that the dose might be too high. These include **excessive panting, pacing, nervousness, increased thirst and urination, a ravenous appetite, or a racing heart rate**. In cats, watch for unusual lethargy or loss of appetite. * **Follow-up:** Your pet will need periodic blood tests to ensure the dose is correct. The timing of the blood draw relative to when you give the pill is very important, so follow your clinic's instructions carefully.
Liothyronine Sodium對我的寵物安全嗎?
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。