Ketorolac
別名: Toradol, Acular
> **Important Safety Warning**: Ketorolac is a very strong pain reliever, but it can cause severe stomach ulcers and kidney damage in pets if not used exactly as directed. - **Strict Dosing**: Never give this medication for longer than prescribed (usually limited to 1-3 days maximum). Do not give more frequently than directed. - **Watch for Side Effects**: Stop the medication immediately and notify your veterinarian if you notice any signs of stomach upset, including loss of appetite, vomiting, diarrhea, **black/tarry stools**, or blood in the stool. - **Behavioral Changes**: Contact your vet if your pet becomes unusually depressed, lethargic, or weak. - **Do Not Mix**: Never give ketorolac with other pain relievers (like aspirin, Rimadyl, Metacam, or steroids) unless specifically instructed by your veterinarian.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As an analgesic
- Anterior uveitis and ulcerative keratitis
- As an analgesic (Mice)
- As an analgesic (Rats)
- As an analgesic
- As an analgesic
- As an analgesic
- Anterior uveitis and ulcerative keratitis
給藥方式
可能的副作用
- Gastrointestinal ulceration and erosion
- Gastrointestinal perforation
- Renal toxicity
- Hepatic toxicity
- Platelet inhibition (increased bleeding risk)
- Local ocular irritation
- Delayed corneal epithelial healing
- Increased intraocular pressure (IOP)
- Corneal 'melting' (keratomalacia) - reported in humans, theoretical risk in animals
注意事項與禁忌
- Active GI ulcers
- History of hypersensitivity to ketorolac
- Pre-existing hematologic, renal, or hepatic disease (relative contraindication)
- Known hypersensitivity to NSAIDs
- Use with extreme caution in patients with deep or progressive corneal ulcers
- Use cautiously in patients with a history of GI ulcers, heart failure (may cause fluid retention), and in geriatric patients. Long-term use (>3 days) is not recommended in dogs due to a high tendency to cause gastric erosion and ulcers. Animals suffering from inflammation secondary to concomitant infection should receive appropriate antimicrobial therapy.
藥物相互作用
- ACE INHIBITORS: Increased risk for nephrotoxicity
- ALPRAZOLAM: Hallucinations reported in some human patients taking with ketorolac
- AMINOGLYCOSIDES (gentamicin, amikacin, etc.): Increased risk for nephrotoxicity
- ANTICOAGULANTS (heparin, LMWH, warfarin): Increased risk for bleeding possible
- ASPIRIN: Increased likelihood of GI adverse effects (blood loss)
- BISPHOSPHONATES (alendronate, etc.): May increase risk for GI ulceration
- CORTICOSTEROIDS: Concomitant administration with NSAIDs may significantly increase the risks for GI adverse effects
- CYCLOSPORINE: May increase risk for nephrotoxicity
- FLUCONAZOLE: May increase NSAID levels
- FLUOXETINE: Hallucinations reported in some human patients taking with ketorolac
- FUROSEMIDE: Ketorolac may reduce the saluretic and diuretic effects of furosemide
常見問題
Ketorolac用於寵物有甚麼用途？
> **Important Safety Warning**: Ketorolac is a very strong pain reliever, but it can cause severe stomach ulcers and kidney damage in pets if not used exactly as directed. - **Strict Dosing**: Never give this medication for longer than prescribed (usually limited to 1-3 days maximum). Do not give more frequently than directed. - **Watch for Side Effects**: Stop the medication immediately and notify your veterinarian if you notice any signs of stomach upset, including loss of appetite, vomiting, diarrhea, **black/tarry stools**, or blood in the stool. - **Behavioral Changes**: Contact your vet if your pet becomes unusually depressed, lethargic, or weak. - **Do Not Mix**: Never give ketorolac with other pain relievers (like aspirin, Rimadyl, Metacam, or steroids) unless specifically instructed by your veterinarian.
Ketorolac對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。