Hydroxyurea
別名: Hydrea, Droxia, Mylocel, Dacrodil, Droxiurea, Hydrine, Litalir, Medroxyurea, Neodrea, Onco-Carbide, Oxeron, Syrea
> **CHEMOTHERAPY HANDLING PRECAUTIONS**: This is an anti-cancer drug. Wear disposable gloves when handling the medication and when cleaning up your pet's urine, feces, or vomit. Pregnant women or individuals trying to conceive should **not** handle this medication. * **Administration**: Give exactly as prescribed by your veterinarian. Do not open, crush, or split capsules unless specifically instructed to do so. * **Side Effects**: Watch for loss of appetite, vomiting, or diarrhea. Contact your vet immediately if you notice unusual bleeding, bruising, lethargy, or signs of infection. * **Nail Changes**: This medication may cause your pet's nails to become brittle or slough off. * **Cats**: Cats are highly sensitive to this drug. Watch closely for breathing difficulties or blue/brown gums, which are medical emergencies.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Polycythemia vera; chronic myelogenous leukemia
- Polycythemia vera
- Polycythemia vera
- Polycythemia vera; chronic myelogenous leukemia
- Polycythemia vera
- Polycythemia vera
- Polycythemia vera
- Chronic myelogenous leukemia
給藥方式
可能的副作用
- Bone marrow depression (anemia, thrombocytopenia, leukopenia)
- GI effects (anorexia, vomiting, diarrhea)
- Stomatitis
- Sloughing of nails
- Alopecia
- Dysuria
- Pulmonary fibrosis
- Methemoglobinemia (especially in cats at high doses >500 mg)
注意事項與禁忌
- Pre-existing severe anemia or bone marrow depression
- History of urate stones
- Current severe infection
- Impaired renal function
- Patients who have recently received other chemotherapy or radiotherapy
- Pregnancy (proven teratogen)
- > **Warning**: Hydroxyurea is a known teratogen and can suppress gonadal function (arrest of spermatogenesis noted in dogs). Use only during pregnancy when benefits outweigh risks. Nursing animals should receive milk replacer. * **Myelotoxicity**: If bone marrow depression occurs, halt therapy until values return to normal. * **Feline Sensitivity**: Cats are at higher risk for bone marrow toxicity and methemoglobinemia; monitor closely.
藥物相互作用
- Bone marrow depressant drugs (e.g., chloramphenicol, flucytosine, amphotericin B, colchicine, other antineoplastics): May cause additive myelosuppression when used concurrently with hydroxyurea.
- Allopurinol: Hydroxyurea may raise serum uric acid levels; allopurinol may be required to control hyperuricemia.
常見問題
Hydroxyurea用於寵物有甚麼用途？
> **CHEMOTHERAPY HANDLING PRECAUTIONS**: This is an anti-cancer drug. Wear disposable gloves when handling the medication and when cleaning up your pet's urine, feces, or vomit. Pregnant women or individuals trying to conceive should **not** handle this medication. * **Administration**: Give exactly as prescribed by your veterinarian. Do not open, crush, or split capsules unless specifically instructed to do so. * **Side Effects**: Watch for loss of appetite, vomiting, or diarrhea. Contact your vet immediately if you notice unusual bleeding, bruising, lethargy, or signs of infection. * **Nail Changes**: This medication may cause your pet's nails to become brittle or slough off. * **Cats**: Cats are highly sensitive to this drug. Watch closely for breathing difficulties or blue/brown gums, which are medical emergencies.
Hydroxyurea對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。