Fosfomycin
別名: Monurol
> **Important:** This medication is typically reserved for highly resistant infections where other antibiotics have failed. Follow your veterinarian's instructions exactly. - **Administration:** If provided as human granules (packets), dissolve the entire contents of a single-dose sachet in 1/2 cup (90-120 mL) of cool or room-temperature water immediately before giving it to your pet. **Do not use hot water.** - **Food:** Can be given with or without food. If it causes stomach upset, giving it with a small treat or meal may help. - **Side Effects:** The most common side effect is diarrhea. Contact your veterinarian if your pet develops severe or bloody diarrhea, vomiting, or loss of appetite. - **Toxicity Warning:** This drug can be highly toxic to the kidneys in **cats**. If your cat was prescribed this medication under special circumstances, monitor them extremely closely for changes in thirst, urination, or lethargy, and attend all scheduled blood test appointments.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Susceptible infections (Investigational)
- Urinary Tract Infection (MDR E. coli)
給藥方式
可能的副作用
- Diarrhea (most common in humans)
- Gastrointestinal upset
- Renal tubular damage / Nephrotoxicity (observed in cats)
注意事項與禁忌
- Young cats (Contraindicated due to nephrotoxicity)
- Adult cats (Relative contraindication; use with extreme caution if at all)
- > **Warning:** Appears to be highly nephrotoxic in cats, causing tubular necrosis and significant increases in serum creatinine. Use is generally contraindicated in felines. - **Renal Impairment:** In humans, renal dysfunction can substantially increase the drug's half-life and reduce urine levels. - **Dosing Strategy:** In humans, this drug is used as a one-time dose; multiple doses do not enhance efficacy and increase the incidence of adverse events. Veterinary protocols are still investigational.
藥物相互作用
- Metoclopramide: Can decrease serum concentrations and reduce urine levels of fosfomycin.
- Prokinetic agents (bethanechol, cisapride, domperidone, ranitidine, laxatives): Theoretical risk of decreasing serum and urine concentrations by increasing GI motility, similar to metoclopramide.
常見問題
Fosfomycin用於寵物有甚麼用途？
> **Important:** This medication is typically reserved for highly resistant infections where other antibiotics have failed. Follow your veterinarian's instructions exactly. - **Administration:** If provided as human granules (packets), dissolve the entire contents of a single-dose sachet in 1/2 cup (90-120 mL) of cool or room-temperature water immediately before giving it to your pet. **Do not use hot water.** - **Food:** Can be given with or without food. If it causes stomach upset, giving it with a small treat or meal may help. - **Side Effects:** The most common side effect is diarrhea. Contact your veterinarian if your pet develops severe or bloody diarrhea, vomiting, or loss of appetite. - **Toxicity Warning:** This drug can be highly toxic to the kidneys in **cats**. If your cat was prescribed this medication under special circumstances, monitor them extremely closely for changes in thirst, urination, or lethargy, and attend all scheduled blood test appointments.
Fosfomycin對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。