Fosfomycin
別名: Monurol
> **Important:** This medication is typically reserved for highly resistant infections where other antibiotics have failed. Follow your veterinarian's instructions exactly. - **Administration:** If provided as human granules (packets), dissolve the entire contents of a single-dose sachet in 1/2 cup (90-120 mL) of cool or room-temperature water immediately before giving it to your pet. **Do not use hot water.** - **Food:** Can be given with or without food. If it causes stomach upset, giving it with a small treat or meal may help. - **Side Effects:** The most common side effect is diarrhea. Contact your veterinarian if your pet develops severe or bloody diarrhea, vomiting, or loss of appetite. - **Toxicity Warning:** This drug can be highly toxic to the kidneys in **cats**. If your cat was prescribed this medication under special circumstances, monitor them extremely closely for changes in thirst, urination, or lethargy, and attend all scheduled blood test appointments.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Susceptible infections (Investigational)
- Urinary Tract Infection (MDR E. coli)
給藥方式
可能的副作用
- Diarrhea (most common in humans)
- Gastrointestinal upset
- Renal tubular damage / Nephrotoxicity (observed in cats)
注意事項與禁忌
- Young cats (Contraindicated due to nephrotoxicity)
- Adult cats (Relative contraindication; use with extreme caution if at all)
- > **Warning:** Appears to be highly nephrotoxic in cats, causing tubular necrosis and significant increases in serum creatinine. Use is generally contraindicated in felines. - **Renal Impairment:** In humans, renal dysfunction can substantially increase the drug's half-life and reduce urine levels. - **Dosing Strategy:** In humans, this drug is used as a one-time dose; multiple doses do not enhance efficacy and increase the incidence of adverse events. Veterinary protocols are still investigational.
藥物相互作用
- Metoclopramide: Can decrease serum concentrations and reduce urine levels of fosfomycin.
- Prokinetic agents (bethanechol, cisapride, domperidone, ranitidine, laxatives): Theoretical risk of decreasing serum and urine concentrations by increasing GI motility, similar to metoclopramide.
常見問題
Fosfomycin用於寵物有甚麼用途？
> **Important:** This medication is typically reserved for highly resistant infections where other antibiotics have failed. Follow your veterinarian's instructions exactly. - **Administration:** If provided as human granules (packets), dissolve the entire contents of a single-dose sachet in 1/2 cup (90-120 mL) of cool or room-temperature water immediately before giving it to your pet. **Do not use hot water.** - **Food:** Can be given with or without food. If it causes stomach upset, giving it with a small treat or meal may help. - **Side Effects:** The most common side effect is diarrhea. Contact your veterinarian if your pet develops severe or bloody diarrhea, vomiting, or loss of appetite. - **Toxicity Warning:** This drug can be highly toxic to the kidneys in **cats**. If your cat was prescribed this medication under special circumstances, monitor them extremely closely for changes in thirst, urination, or lethargy, and attend all scheduled blood test appointments.
Fosfomycin對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。