Fluconazole
別名: Diflucan
- **Patience is Key:** Fungal infections take a long time to clear. Treatment often lasts for several weeks to months. Do not stop the medication early even if your pet looks better, as the infection can relapse. - **Administration:** Fluconazole is very well absorbed whether given with food or on an empty stomach. - **Watch for Side Effects:** While generally very safe, watch for loss of appetite, vomiting, or diarrhea. Contact your veterinarian if these occur. - **Cost:** Because treatment is prolonged, the cost can add up, though generic options have made it more affordable.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Nasal or dermal cryptococcosis
- CNS, intraocular, or multisystemic cryptococcosis
- CNS, intraocular or multisystemic mycoses
- Cryptococcosis
- Cryptococcosis
- C. immitis infection or Candida bacteremia
- Fungal keratitis
- Candidiasis (cockatoos, parrots)
- Candidiasis (cockatiels)
- Alternate treatment of aspergillosis
- General (Rabbits)
- Cryptococcosis, candidiasis, systemic mycoses, nasal aspergillosis
- Fungal meningitis
給藥方式
可能的副作用
- Inappetence
- Vomiting
- Diarrhea
- Hepatotoxicity (rare)
- Headache (humans)
- Increased liver enzymes (humans)
- Exfoliative skin disorders (humans)
- Thrombocytopenia (humans)
- Nausea
- Diarrhoea
- Hepatotoxicity
注意事項與禁忌
- Hypersensitivity to fluconazole or other azole antifungals
- Budgerigars (reportedly toxic)
- Pregnant animals
- Lactating animals
- Use with caution in patients with hepatic impairment. Because fluconazole is eliminated primarily by the kidneys, doses or dosing intervals may need to be adjusted in patients with renal impairment. Safety during pregnancy has not been established (FDA Category C); use with caution in nursing dams as it is excreted in milk. Reportedly toxic to budgerigars.
藥物相互作用
- Amphotericin B: May be antagonistic against Aspergillus or Candida; clinical importance unclear
- Buspirone: Plasma concentrations of buspirone may be elevated
- Cisapride: May increase cisapride levels and the possibility for toxicity
- Corticosteroids: May inhibit the metabolism of corticosteroids; potential for increased adverse effects
- Cyclophosphamide: May inhibit the metabolism of cyclophosphamide and its metabolites; potential for increased toxicity
- Cyclosporine: Increases cyclosporine levels; dosage of cyclosporine may need to be decreased by 29%-51%
- Diuretics, Thiazides: Increased fluconazole concentrations
- Fentanyl/Alfentanil: May increase fentanyl levels
- Midazolam: Increased midazolam levels and effects
- NSAIDs: May increase NSAID plasma levels; increased risk for adverse effects
- Quinidine: Increased risk for cardiotoxicity
常見問題
Fluconazole用於寵物有甚麼用途？
- **Patience is Key:** Fungal infections take a long time to clear. Treatment often lasts for several weeks to months. Do not stop the medication early even if your pet looks better, as the infection can relapse. - **Administration:** Fluconazole is very well absorbed whether given with food or on an empty stomach. - **Watch for Side Effects:** While generally very safe, watch for loss of appetite, vomiting, or diarrhea. Contact your veterinarian if these occur. - **Cost:** Because treatment is prolonged, the cost can add up, though generic options have made it more affordable.
Fluconazole對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。