Doxapram
別名: Dopram-V, Respiram, Dopram, Docatone, Doxapril
Doxapram is an emergency and anesthetic adjunct medication used **exclusively in a hospital setting** under direct professional supervision. - Your veterinarian may use this medication to help stimulate your pet's breathing as they wake up from anesthesia. - It is also frequently used during specific diagnostic procedures, such as evaluating the function of the larynx (voice box) in dogs suspected of having laryngeal paralysis. - Because it stimulates the central nervous system, your pet will be closely monitored for changes in heart rate, breathing rate, and neurological status while receiving this drug.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Gas anesthesia recovery
- Barbiturate anesthesia recovery
- To initiate or stimulate respirations in neonates after caesarian section or dystocia
- To stimulate respiratory function in neonates
- Primary apnea in asphyxic calves when intubation and mechanical ventilation are not feasible
- Primary apnea in newborn calves
- Halothane, methoxyflurane anesthesia recovery
- Chloral hydrate ± magnesium sulfate anesthesia recovery
- Adjunctive treatment to stimulate respirations in foals with sepsis or hypoxic-ischemic encephalopathy
- Respiratory depression
- Respiratory depression (Rabbits)
- Respiratory depression (Rodents)
給藥方式
可能的副作用
- Hypertension
- Arrhythmias
- Tachycardia
- Seizures (at high doses)
- Hyperventilation leading to respiratory alkalosis
- Increased myocardial oxygen demand
- Reduced cerebral blood flow
- Skeletal muscle hyperactivity
注意事項與禁忌
- Patients receiving mechanical ventilation
- Hypersensitivity to doxapram
- Seizure disorders
- Head trauma or cerebrovascular accidents (CVA)
- Uncompensated heart failure
- Severe hypertension
- Respiratory failure secondary to neuromuscular disorders
- Airway obstruction
- Pulmonary embolism
- Pneumothorax
- Acute asthma
- Dyspnea
- Hypoxia not associated with hypercapnia
- Premature calves or patients with clinical signs of lung immaturity
藥物相互作用
- General Anesthetics (e.g., halothane, enflurane): Doxapram may increase epinephrine release and sensitize the myocardium to catecholamines. Use should be delayed for ~10 minutes after discontinuing these anesthetics.
- Muscle Relaxants: Doxapram may mask the effects of muscle relaxant drugs.
- Sympathomimetic Agents: Additive pressor (blood pressure increasing) effects may occur.
常見問題
Doxapram用於寵物有甚麼用途？
Doxapram is an emergency and anesthetic adjunct medication used **exclusively in a hospital setting** under direct professional supervision. - Your veterinarian may use this medication to help stimulate your pet's breathing as they wake up from anesthesia. - It is also frequently used during specific diagnostic procedures, such as evaluating the function of the larynx (voice box) in dogs suspected of having laryngeal paralysis. - Because it stimulates the central nervous system, your pet will be closely monitored for changes in heart rate, breathing rate, and neurological status while receiving this drug.
Doxapram對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。