Doxapram
別名: Dopram-V, Respiram, Dopram, Docatone, Doxapril
Doxapram is an emergency and anesthetic adjunct medication used **exclusively in a hospital setting** under direct professional supervision. - Your veterinarian may use this medication to help stimulate your pet's breathing as they wake up from anesthesia. - It is also frequently used during specific diagnostic procedures, such as evaluating the function of the larynx (voice box) in dogs suspected of having laryngeal paralysis. - Because it stimulates the central nervous system, your pet will be closely monitored for changes in heart rate, breathing rate, and neurological status while receiving this drug.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Gas anesthesia recovery
- Barbiturate anesthesia recovery
- To initiate or stimulate respirations in neonates after caesarian section or dystocia
- To stimulate respiratory function in neonates
- Primary apnea in asphyxic calves when intubation and mechanical ventilation are not feasible
- Primary apnea in newborn calves
- Halothane, methoxyflurane anesthesia recovery
- Chloral hydrate ± magnesium sulfate anesthesia recovery
- Adjunctive treatment to stimulate respirations in foals with sepsis or hypoxic-ischemic encephalopathy
- Respiratory depression
- Respiratory depression (Rabbits)
- Respiratory depression (Rodents)
給藥方式
可能的副作用
- Hypertension
- Arrhythmias
- Tachycardia
- Seizures (at high doses)
- Hyperventilation leading to respiratory alkalosis
- Increased myocardial oxygen demand
- Reduced cerebral blood flow
- Skeletal muscle hyperactivity
注意事項與禁忌
- Patients receiving mechanical ventilation
- Hypersensitivity to doxapram
- Seizure disorders
- Head trauma or cerebrovascular accidents (CVA)
- Uncompensated heart failure
- Severe hypertension
- Respiratory failure secondary to neuromuscular disorders
- Airway obstruction
- Pulmonary embolism
- Pneumothorax
- Acute asthma
- Dyspnea
- Hypoxia not associated with hypercapnia
- Premature calves or patients with clinical signs of lung immaturity
藥物相互作用
- General Anesthetics (e.g., halothane, enflurane): Doxapram may increase epinephrine release and sensitize the myocardium to catecholamines. Use should be delayed for ~10 minutes after discontinuing these anesthetics.
- Muscle Relaxants: Doxapram may mask the effects of muscle relaxant drugs.
- Sympathomimetic Agents: Additive pressor (blood pressure increasing) effects may occur.
常見問題
Doxapram用於寵物有甚麼用途？
Doxapram is an emergency and anesthetic adjunct medication used **exclusively in a hospital setting** under direct professional supervision. - Your veterinarian may use this medication to help stimulate your pet's breathing as they wake up from anesthesia. - It is also frequently used during specific diagnostic procedures, such as evaluating the function of the larynx (voice box) in dogs suspected of having laryngeal paralysis. - Because it stimulates the central nervous system, your pet will be closely monitored for changes in heart rate, breathing rate, and neurological status while receiving this drug.
Doxapram對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。