多沙普侖
別名: Dopram-V, Respiram, Dopram, Docatone, Doxapril
藥物類別: CNS/Respiratory Stimulant
多沙普侖是一種急救與麻醉輔助藥物，**僅限在動物醫院內**由專業人員直接監督下使用。 - 您的獸醫師可能會在寵物從麻醉中甦醒時，使用此藥物來幫助刺激其呼吸。 - 它也常用於特定的診斷程序中，例如評估懷疑患有喉頭麻痺的狗狗的喉部（聲匣）功能。 - 由於它會刺激中樞神經系統，在給予此藥物期間，醫療團隊會密切監測您寵物的心跳速率、呼吸頻率以及神經系統狀態。
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Gas anesthesia recovery
- Barbiturate anesthesia recovery
- To initiate or stimulate respirations in neonates after caesarian section or dystocia
- To stimulate respiratory function in neonates
- Primary apnea in asphyxic calves when intubation and mechanical ventilation are not feasible
- Primary apnea in newborn calves
- Halothane, methoxyflurane anesthesia recovery
- Chloral hydrate ± magnesium sulfate anesthesia recovery
- Adjunctive treatment to stimulate respirations in foals with sepsis or hypoxic-ischemic encephalopathy
- Respiratory depression
- Respiratory depression (Rabbits)
- Respiratory depression (Rodents)
- Respiratory depression (Mice, Rats, Gerbils, Hamsters)
- Respiratory depression (Guinea pigs)
- Respiratory depression (Chinchillas)
- Gas anesthesia recovery
- Barbiturate anesthesia recovery
- To initiate or stimulate respirations in neonates after caesarian section or dystocia
- To stimulate respiratory function in neonates
- To assess laryngeal function
- To stimulate respiration after general anesthesia
給藥方式
IVIMSCSublingualUmbilical vein
可能的副作用
- Hypertension
- Arrhythmias
- Tachycardia
- Seizures (at high doses)
- Hyperventilation leading to respiratory alkalosis
- Increased myocardial oxygen demand
- Reduced cerebral blood flow
- Skeletal muscle hyperactivity
注意事項與禁忌
- Patients receiving mechanical ventilation
- Hypersensitivity to doxapram
- Seizure disorders
- Head trauma or cerebrovascular accidents (CVA)
- Uncompensated heart failure
- Severe hypertension
- Respiratory failure secondary to neuromuscular disorders
- Airway obstruction
- Pulmonary embolism
- Pneumothorax
- Acute asthma
- Dyspnea
- Hypoxia not associated with hypercapnia
- Premature calves or patients with clinical signs of lung immaturity
- Use with extreme caution in patients with a history of asthma, arrhythmias, tachycardias, cerebral edema, increased CSF pressure, pheochromocytoma, or hyperthyroidism. Doxapram is NOT a substitute for aggressive artificial (mechanical) respiratory support. Avoid IV extravasation or using a single injection site for a prolonged period. Repeated IV doses in neonates should be administered with caution because the commercial product contains benzyl alcohol as a preservative.
藥物相互作用
- General Anesthetics (e.g., halothane, enflurane): Doxapram may increase epinephrine release and sensitize the myocardium to catecholamines. Use should be delayed for ~10 minutes after discontinuing these anesthetics.
- Muscle Relaxants: Doxapram may mask the effects of muscle relaxant drugs.
- Sympathomimetic Agents: Additive pressor (blood pressure increasing) effects may occur.
常見問題
多沙普侖用於寵物有甚麼用途？
多沙普侖是一種急救與麻醉輔助藥物，僅限在動物醫院內由專業人員直接監督下使用。 - 您的獸醫師可能會在寵物從麻醉中甦醒時，使用此藥物來幫助刺激其呼吸。 - 它也常用於特定的診斷程序中，例如評估懷疑患有喉頭麻痺的狗狗的喉部（聲匣）功能。 - 由於它會刺激中樞神經系統，在給予此藥物期間，醫療團隊會密切監測您寵物的心跳速率、呼吸頻率以及神經系統狀態。
多沙普侖對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。