Dexmedetomidine
別名: Dexdomitor, Precedex
* **Professional Use Only:** This drug should be administered and monitored by veterinary professionals only. * **Post-Sedation Care:** Keep your pet in a quiet, warm, and comfortable environment after they return home. They may remain slightly groggy. * **Risks:** Be aware of potential adverse effects, particularly if your dog is older or has pre-existing heart, liver, or kidney conditions. * **Diet:** Follow your veterinarian's instructions regarding fasting before the procedure and when to resume feeding afterward.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Sedation and analgesia
- Sedation and analgesia
- Preanesthetic
- Premed prior to propofol or face mask induction (geriatric/renal/liver dysfunction)
- Slightly heavier sedation for radiographic procedures (ASA II or III)
- Minor surgery, Penn hip or OFA-types of radiographic procedures
- Surgical plane of anesthesia for OHE, castration, or abdominal surgery
- Immobilizing extremely fractious dogs and wolf-hybrid dogs
- Post-operative pain management in critically ill dogs
給藥方式
可能的副作用
- Bradycardia (profound)
- Occasional AV blocks
- Decreased respiration / Apnea
- Hypothermia
- Urination
- Vomiting
- Hyperglycemia
- Pain on injection (IM)
- Prolonged sedation
- Paradoxical excitation
- Hypersensitivity
- Pulmonary edema
- Death from circulatory failure (rare)
- Muscle tremors
注意事項與禁忌
- Cardiovascular disease
- Respiratory disorders
- Liver or kidney diseases
- Shock or severe debilitation
- Stress due to extreme heat, cold, or fatigue
- Puppies < 16 weeks (US label) or < 6 months (UK label)
- Kittens < 12 weeks (US label) or < 5 months (UK label)
- Hypersensitivity to the active substance
- > **Cardiovascular Warning:** Due to pronounced cardiovascular effects (bradycardia, vasoconstriction), only clinically healthy dogs and cats should be treated. * **Seizure Disorders:** Use with caution in animals with or prone to developing seizures; may lower the seizure threshold. * **Ocular Care:** Blinking may be impaired and tear production reduced; **eye lubricants** should be applied during sedation. * **Pregnancy/Nursing:** Not recommended for use in pregnant or breeding animals unless benefits clearly outweigh risks (FDA Category C). Safe use during nursing is not established.
藥物相互作用
- Anesthetics, Opiates, Sedative/Hypnotics: Effects may be additive; dosage reduction of one or both agents may be required. General anesthetic requirements may be reduced between 30-60%.
- Atropine, Glycopyrrolate: Can significantly increase arterial blood pressure and heart rate; use together is not recommended in dogs due to increased cardiac workload.
- Epinephrine: Possesses alpha agonist effects; do not use to treat cardiac effects caused by dexmedetomidine.
- Yohimbine: May reverse the effects, but atipamezole is preferred for clinical use.
常見問題
Dexmedetomidine用於寵物有甚麼用途？
* **Professional Use Only:** This drug should be administered and monitored by veterinary professionals only. * **Post-Sedation Care:** Keep your pet in a quiet, warm, and comfortable environment after they return home. They may remain slightly groggy. * **Risks:** Be aware of potential adverse effects, particularly if your dog is older or has pre-existing heart, liver, or kidney conditions. * **Diet:** Follow your veterinarian's instructions regarding fasting before the procedure and when to resume feeding afterward.
Dexmedetomidine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。